Welcome to LookChem.com Sign In|Join Free

Product Name

  • or
Home > Products > 

Melphalan hydrochloride
Basic Information Post buying leads Suppliers
Basic InformationSuppliers
  • Name Melphalan hydrochloride
  • EINECSN/A
  • CAS No. 3223-07-2
  • Densityg/cm3
  • PSA66.56000
  • LogP3.42730
  • SolubilityN/A
  • Melting Point175-178 °C
  • FormulaC13H18 Cl2 N2 O2 . Cl H
  • Boiling Point473.1°Cat760mmHg
  • Molecular Weight341.665
  • Flash Point239.9°C
  • Transport InformationN/A
  • AppearanceN/A
  • SafetyDeadly poison by intravenous route. Human systemic effects by ingestion: nausea and vomiting. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits very toxic fumes of Cl−, NOx, and HCl.
  • Risk CodesN/A
  • Molecular Structure
    Molecular Structure of 3223-07-2 (4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE)
  • Hazard SymbolsN/A
  • SynonymsN/A

Melphalan hydrochloride Chemical Properties

IUPAC:  2-Amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid hydrochloride 
 L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine monohydrochloride CAS NO.of  3223-07-2 is also called for  AI3-26377 ; Alanine nitrogen mustard hydrochloride ; Alkeran ; Alkeran hydrochloride ; CB 3025 hydrochloride ; L-Phenylalanine mustard hydrochloride ; L-Sarcolysine hydrochloride ; Melfalan hydrochloride ; Melphalan HCl ; Melphalan hydrochloride ; Phenylalanine mustard hydrochloride ; SK 15673 ; UNII-1VXP4V453T and so on.
CAS: 3223-07-2
Molecula Formula: C13H19Cl3N2O2
Molecular Weight: 341.66
EINECS: 205-726-3
ACD/LogP: 1.80 
ACD/LogD (pH 5.5): -0.72 
ACD/LogD (pH 7.4): -0.71 
ACD/BCF (pH 5.5): 1 
ACD/BCF (pH 7.4): 1 
ACD/KOC (pH 5.5): 1 
ACD/KOC (pH 7.4): 1 
H bond acceptors: 4 
H bond donors: 3 
Freely Rotating Bonds: 9
Heavy Atom Count: 20
Formal Charge: 0
Complexity: 265
Isotope Atom Count: 0
Defined Atom StereoCenter Count: 0
Undefined Atom StereoCenter Count: 1
Defined Bond StereoCenter Count: 0
Undefined Bond StereoCenter Count: 0
Covalently-Bonded Unit Count: 2
Flash Point: 239.9°C 
Enthalpy of Vaporization: 77.55 kJ/mol 
Boiling Point: 473.1°C at 760 mmHg 
Vapour Pressure: 9.33E-10 mmHg at 25°C 
The molecular structure of  L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine monohydrochloride CAS NO.of  3223-07-2:

Melphalan hydrochloride Uses

 L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine monohydrochloride (CAS NO.3223-07-2) is used as antineoplastic agent and myeloablative agonist.

Melphalan hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 430ug/kg (0.43mg/kg) BLOOD: LEUKOPENIA

BLOOD: THROMBOCYTOPENIA

BLOOD: OTHER CHANGES		 Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 201, 1965.
dog LDLo oral 4mg/kg (4mg/kg) BLOOD: AGRANULOCYTOSIS

BLOOD: CHANGES IN BONE MARROW NOT INCLUDED ABOVE		 National Technical Information Service. Vol. PB229-000,
human TDLo oral 1200ug/kg/5D- (1.2mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING Cancer Chemotherapy Reports, Part 1. Vol. 57, Pg. 369, 1973.
monkey LDLo intravenous 430ug/kg (0.43mg/kg) BLOOD: LEUKOPENIA

BLOOD: AGRANULOCYTOSIS

BLOOD: OTHER CHANGES		 Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 201, 1965.
mouse LD50 intravenous 23mg/kg (23mg/kg)   National Technical Information Service. Vol. PB84-162486,

Melphalan hydrochloride Safety Profile

Deadly poison by intravenous route. Human systemic effects by ingestion: nausea and vomiting. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits very toxic fumes of Cl−, NOx, and HCl.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 3223-07-2
Related Products

Hot Products

Post a RFQ