Derivatization reagent

Derivatization reagents are chemical compounds used in analytical chemistry to modify the structure of analytes before analysis, enhancing their detectability or improving the separation process. These reagents react with functional groups present in the analyte molecules to form derivatives that are more stable, volatile, or suitable for specific detection methods such as gas chromatography (GC) or liquid chromatography (LC). Derivatization reagents can introduce chromophores, fluorophores, or other chemical moieties that alter the physical or chemical properties of the analyte, facilitating sensitive detection or enabling differentiation of closely related compounds.