Serine Protease Inhibitors
Serine protease inhibitors are molecules designed to block the activity of serine proteases, a class of enzymes crucial for various biological processes, including digestion, blood clotting, immune response, and apoptosis. Serine proteases function by cleaving peptide bonds in proteins, thereby regulating their activity or enabling their degradation. Inhibiting serine proteases can disrupt these processes, potentially altering cellular functions and physiological responses. These inhibitors are studied for their therapeutic potential in treating conditions where serine protease activity is dysregulated, such as inflammatory diseases, thrombosis, and certain cancers. Development of selective serine protease inhibitors is critical to target specific enzymes involved in disease pathways while minimizing off-target effects on normal physiological processes, aiming to improve treatment efficacy and safety profiles.
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