45214-91-3

Basic information

• Product Name: BOC-GLU(OME)-OH
• Synonyms: BOC-GLU(OME)-OH;BOC-L-GLUTAMIC ACID GAMMA-METHYL ESTER;N-ALPHA-T-BUTOXYCARBONYL-L-GLUTAMIC ACID GAMMA-METHYL ESTER;BOC-L-GLUTAMIC ACID Y-METHYLESTER;N-ALPHA-BOC-L-GLUTAMIC ACID GAMMA-METHYL ESTER;N-Boc-L-glutamic acid-5-methylester;(S)-2-(tert-butoxycarbonylamino)-5-methoxy-5-oxopentanoic acid;Boc-Glu(OMe)-OH Boc-L-glutaMic acid γ-Methyl ester
• CAS NO: 45214-91-3
• Molecular Formula: C₁₁H₁₉NO₆
• Molecular Weight: 261.27
• Mol File: 45214-91-3.mol
• Article Data: 33

Chemical Properties

• Boiling Point: 428.35 °C at 760 mmHg
• Flash Point: 212.859 °C
• Appearance: White/Solid
• Density: 1.183 g/cm³
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Sparingly), Methanol (Slightly)
• PKA: 3.82±0.10(Predicted)
• CAS DataBase Reference: BOC-GLU(OME)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-GLU(OME)-OH(45214-91-3)
• EPA Substance Registry System: BOC-GLU(OME)-OH(45214-91-3)

Safety Data

• Hazardous Substances Data: 45214-91-3(Hazardous Substances Data)

Usage

Uses

N-Boc-L-glutamic Acid 5-Methyl Ester is an intermediate used in the synthesis of Isodesmosine Chloride Hydrate (Synthetic) (I815051), which is a component of elastin and also it is extremely hygroscopic and must be stored over a desiccant such as silica gel.

Upstream product

• 24277-38-1 (S)-(-)-1-tert-butyl-5-methyl-<(2-tert-butoxycarbonyl)amino>pentanedioate 
• 56-86-0 L-glutamic acid 
• 6461-04-7 (R)-2-amino-5-methoxy-5-oxopentanoic acid 
• 41840-28-2 S-tert-butoxycarbonyl-4,6-dimethyl-2-mercaptopyrimidine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1499-55-4 glutamic acid γ-methyl ester 
• 27025-22-5 D-glutamic acid-5-methyl ester; hydrochloride 
• 6893-26-1 D-Glutamic acid 
• 34619-03-9 tert-butyldicarbonate 
• 1499-55-4 L-glutamic acid 5-methyl ester 
• 138-15-8 l-glutamic acid hydrochloride 
• 30924-93-7 Boc-Glu-OBn 
• 132245-78-4 (S)-2-tert-butoxycarbonylaminopentanedioic acid 1-benzyl ester 5-methyl ester 
• 3077-51-8 γ-methyl L-glutamate hydrochloride 

Downstream Products

• 91229-99-1 N-(Benzyloxy)-N^α-(tert-butoxycarbonyl)-L-glutamamide γ-methyl ester 
• 91279-50-4 1-(benzyloxy)-3-<(tert-butyloxycarbonyl)amino>-2-piperidone 
• 91229-98-0 1-(benzyloxy)-5-<(tert-butyloxycarbonyl)amino>-piperidone 
• 26048-86-2 2-Benzyloxycarbamoyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 91229-96-8 (4S)-N-benzyloxy-4-(N-tert-butoxycarbonyl)amino-5-hydroxypentanamide 
• 91229-94-6 (S)-O-benzyl 2-<(tert-butyloxycarbonyl)amino>-5-hydroxypentanohydroxamate 
• 91229-93-5 O^α-benzyl N^α-(tert-butyloxycarbonyl)-L-glutamic acid α-hydroxamate 
• 91229-95-7 O^α-benzyl N^α-(tert-butyloxycarbonyl)-γ-(2-thioxo-1,3-thiazolidin-3-yl)-L-glutamic acid α-hydroxamate 
• 1218778-29-0 C₂₀H₂₉N₃O₆ 
• 1333218-59-9 3-[(4S)-4-amino-4-[(2-phenylethyl)carbamoyl]butanamide]-5-chloro-2-hydroxybenzene-1-sulfonic acid 
• 76379-02-7 t-butoxycarbonyl-D-glutamic acid γ-methyl ester dicyclohexylamine salt 
• 162610-71-1 N-<3-<1-(Benzyloxy)-5,6-dimethyl-2-oxo-1,2-dihydropyraz-3-yl>propanoyl>-L-leucyl-β-alanine O-succinimide ester 
• 162610-70-0 N-<3-<1-(Benzyloxy)-5,6-dimethyl-2-oxo-1,2-dihydropyraz-3-yl>propanoyl>-L-alanyl-β-alanine O-succinimide ester 
• 162610-67-5 N-<3-<1-(Benzyloxy)-5,6-dimethyl-2-oxo-1,2-dihydropyraz-3-yl>propanoyl>-L-leucyl-β-alanine methyl ester 

Relevant articles and documents

A PROCESS FOR THE PREPARATION OF L-GLUTAMINE

The present invention relates to a process for the preparation of L-Glutamine of Formula (I). The present invention also relates to an improved process for the purification of L-Glutamine of Formula (I) having specific bulk density and Hausner ratio.

Constrained Cyclic β,γ-Diamino Acids from Glutamic Acid: Synthesis of Both Diastereomers and Unexpected Kinetic Resolution

We describe here an efficient synthesis of both diastereomers of cyclic β,γ-diamino acids starting from l-glutamic acid, based on the Blaise reaction. We show that by changing the protecting group, we can access either the five-membered-ring lactam, which

Synthesis of ortho-carboranyl derivatives of (S)-asparagine and (S)-glutamine

(S)-Asparagine and (S)-glutamine ortho-carboranyl derivatives with free amino and carboxy groups in the α-position were synthesized. By an example of Nγ-(1,2-dicarba-closo-dodecarboran-3-yl)-(S)-glutamine it was demonstrated that the developed synthetic approach carboranyl derivatives of amino acids allowed the preparation of optically pure isomers.