145586-17-0Relevant articles and documents
Homophymamide A, Heterodetic Cyclic Tetrapeptide from a Homophymia sp. Marine Sponge: A Cautionary Note on Configurational Assignment of Peptides That Contain a Ureido Linkage
Kanki, Daichi,Nakamukai, Shohei,Ogura, Yusuke,Takikawa, Hirosato,Ise, Yuji,Morii, Yasuhiro,Yamawaki, Nobuhiro,Takatani, Tomohiro,Arakawa, Osamu,Okada, Shigeru,Matsunaga, Shigeki
, p. 1848 - 1853 (2021/06/28)
A previously unreported heterodetic cyclic peptide, homophymamide A (1), was isolated from a Homophymia sp. marine sponge. The structure of homophymamide A was determined to be a lower homologue of anabaenopeptins by spectroscopic analysis, chemical degradation, and chemical synthesis. Analysis of the acidic hydrolysate showed that the racemization of Lys took place, leading us to pose a cautionary note on the configurational assignment of peptides that contain a ureido bond.