99902-35-9 Usage
Description
(R)-3-hydroxy-5-phenyl-1-pentyne is a chiral alkyne compound with the molecular formula C11H12O. It features a pentynyl chain with a hydroxyl group and a phenyl group attached to it. The (R) configuration denotes the specific arrangement of substituent groups around the stereocenter, which is crucial for its properties and potential applications.
Uses
Used in Organic Synthesis:
(R)-3-hydroxy-5-phenyl-1-pentyne is used as a building block in organic synthesis for the creation of more complex molecules. Its unique structure, including the alkyne and phenyl groups, allows for a variety of chemical reactions, making it a versatile component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
(R)-3-hydroxy-5-phenyl-1-pentyne is used as an intermediate in the development of pharmaceutical compounds. Its chiral nature and functional groups can be exploited to create enantiomerically pure drugs, which are essential for ensuring the desired therapeutic effects and minimizing side effects.
Used in Chemical Industry:
(R)-3-hydroxy-5-phenyl-1-pentyne is utilized as a specialty chemical in various applications within the chemical industry. Its properties may be harnessed for the production of materials with specific characteristics, such as coatings, adhesives, or polymers with tailored properties.
Used in Research:
(R)-3-hydroxy-5-phenyl-1-pentyne is used as a subject of research to explore the properties and reactivity of alkynes and chiral compounds. Understanding its behavior in chemical reactions can lead to the discovery of new synthetic routes and applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 99902-35-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,9,0 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 99902-35:
(7*9)+(6*9)+(5*9)+(4*0)+(3*2)+(2*3)+(1*5)=179
179 % 10 = 9
So 99902-35-9 is a valid CAS Registry Number.
99902-35-9Relevant articles and documents
Sc(OTf)3-catalyzed [3 + 2]-cycloaddition of nitrones with ynones
He, Chun-Ting,Han, Xiao-Li,Zhang, Yan-Xue,Du, Zhen-Ting,Si, Chang-Mei,Wei, Bang-Guo
supporting information, p. 457 - 466 (2021/01/29)
An efficient approach to access functionalized (2,3-dihydroisoxazol-4-yl) ketones has been developed by reacting nitrones 4 with ynones 7 or terminal ynones 10 in a one-pot fashion. The reaction went through a formal Sc(OTf)3-catalyzed [3 + 2]-cycloaddition process to generate a number of functionalized (2,3-dihydroisoxazol-4-yl) ketones 11aa-11aw, 11ba-11la and 12aa-12ae in moderate to good yields. This journal is
Synthesis of Difluorinated Dihydrobenzo[de]chromenes via Rh(III)-Catalysed C-H Couplings of 1-Naphthols with Gem-Difluoromethylene Alkynes
Li, Liping,Zhong, Xiuhua,Xu, Jiali,Gao, Hui,Zhou, Zhi,Yi, Wei
supporting information, p. 1352 - 1357 (2021/02/01)
The Rh(III)-catalysed C?H couplings of 1-naphthols with gem-difluoromethylene alkynes have been realized for the direct construction of difluorinated dihydrobenzo[de]chromenes with broad substrate/functional group compatibility and good regio-/chemoselect
Transition-Metal-Free Synthesis of Electron Rich 1,3-Dienes via Base Promoted Isomerization of Propargylic Ethers
Liu, Chunxiang,Deng, Guogang,Li, Xin,Xu, Yiren,Yu, Kaili,Chen, Wen,Zhang, Hongbin,Yang, Xiaodong
, p. 483 - 487 (2020/01/25)
Herein, a novel and scalable synthesis of electron rich 1,3-dienes based on KOtBu mediated isomerization of propargylic ether derivatives was developed. This new process features easy handling reaction conditions, transition-metal-free isomerization, high isolated yields, and most of all, it could be used for modification of natural products at late stage functionalizations.
