965-50-4

Basic information

• Product Name: Benzenepropanamide, N-(4-methoxyphenyl)-b-oxo-
• CAS NO: 965-50-4
• Molecular Formula: C16H15NO3
• Molecular Weight: 269.3
• Mol File: 965-50-4.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzenepropanamide, N-(4-methoxyphenyl)-b-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamide, N-(4-methoxyphenyl)-b-oxo-(965-50-4)
• EPA Substance Registry System: Benzenepropanamide, N-(4-methoxyphenyl)-b-oxo-(965-50-4)

Safety Data

• Hazardous Substances Data: 965-50-4(Hazardous Substances Data)

Upstream product

• 10507-69-4 4-methoxybenzohydroxamic acid 
• 98-86-2 acetophenone 
• 19226-37-0 3-(4-methoxyphenyl)-5H-1,4,2-dioxazol-5-one 
• 5382-38-7 2-cyano-N-(4-methoxyphenyl)acetamide 
• 98-80-6 phenylboronic acid 
• 5437-98-9 4'-methoxyacetoacetanilide 
• 1074-12-0 phenylglyoxal hydrate 
• 55991-67-8 5-phenylfuran-2,3-dione 
• 77092-12-7 6-phenyl-2,2-dimethyl-1,3-dioxin-4-one 
• 104-94-9 4-methoxy-aniline 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 

Downstream Products

• 104-94-9 4-methoxy-aniline 
• 716-79-0 2-phenyl-1H-benzoimidazole 
• 1449570-47-1 5-((E)-hex-1-enyl)-N-(4-methoxyphenyl)-2-methylfuran-3-carboxamide 
• 120243-00-7 2-(4-ethyl-1-piperazinyl)-6-methoxy-4-phenylquinoline 
• 120243-01-8 2-(4-ethyl-1-piperazinyl)-6-hydroxy-4-phenylquinoline 
• 120242-99-1 2-chloro-6-methoxy-4-phenylquinoline 
• 80392-90-1 6-Hydroxy-2-imino-1-(4-methoxy-phenyl)-4-phenyl-1,2-dihydro-pyridine-3-carbonitrile 
• 80392-86-5 2-Hydroxy-6-(4-methoxy-phenylamino)-4-phenyl-nicotinonitrile 
• 80392-82-1 2-{Amino-[6-(4-methoxy-phenylamino)-2-oxo-4-phenyl-2H-pyridin-(3Z)-ylidene]-methyl}-malononitrile 
• 1227-44-7 N,N'-bis(4-methoxyphenyl)urea 
• 98-86-2 acetophenone 

Relevant articles and documents

NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF

A class of compounds that bind to fatty acid binding protein (FABP4) and modulate adipocyte metabolism to drive enhanced glucose utilization, as well as pharmaceutical compositions comprising the class of compounds, in combination with a pharmaceutically acceptable diluent or carrier, and optionally, further in combination with a therapeutically active agent, and the use of these compounds in medicine and for the preparation of a medicament in the treatment of disorders acting on the FABP4.

Palladium catalysed hydrolysis-free arylation of aliphatic nitriles for the synthesis of 4-arylquinolin-2-one/pyrazolone derivatives

Palladium catalysed addition of arylboronic acid to the readily available 2-cyano-(N-aryl)-acetamide or ethyl-2-cyanoacetate followed by subsequent reaction transform them into the biologically significant 4-arylquinolin-2-one or pyrazolone derivatives. The reaction conditions are robust enough to prevent the hydrolysis of ester/amide moiety during arylation. In addition, the unactivated nitrile moiety in the acetonitrile also converted to the corresponding acetophenone derivative.

Silver(I)-catalyzed tandem approach to β-oxo amides

A facile and efficient AgI-catalytic approach is reported for the first time to synthesize β-oxo amides from β-oxo esters a with broad substrate scope in good to excellent yields. Crossover and in situ NMR studies confirmed that the reaction occurred through a new pathway and not by the traditional condensation reaction. The key advantages of this method are the readily available starting materials, the air-stable reaction, the simple protocol, and the environmental friendliness. A new, catalytic approach to the synthesis of β-oxo amides from β-oxo esters with a broad substrate scope in good to excellent yields was developed. In situ NMR spectroscopy and crossover experiments confirmed the reaction mechanism.