912643-33-5Relevant articles and documents
An alternate synthesis of enantiomerically pure levetiracetam (Keppra)
Mujahid, M.,Mujumdar, P.,Sasikumar, M.,Kunte, S. S.,Muthukrishnan, M.
, p. 1512 - 1515,4 (2012/12/12)
A simple and efficient synthesis of levetiracetam has been achieved with high enantiopurity (>99%) starting from commercially available benzyl glycidyl ether. The method is amenable for industrial scale-up.
A short enantioselective synthesis of the antiepileptic agent, levetiracetam based on proline-catalyzed asymmetric α-aminooxylation
Kotkar, Shriram P.,Sudalai, Arumugam
, p. 6813 - 6815 (2007/10/03)
An efficient enantioselective synthesis of a new antiepileptic drug, levetiracetam is described, in high optical purity (>99.5% ee), using proline-catalyzed α-aminooxylation of n-butyraldehyde as the key step.
