909566-58-1Relevant articles and documents
Compositions and methods for the treatment of epilepsy
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Page/Page column 37, (2016/04/20)
The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I or formula II; and methods for treating or preventing neurological diseases may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of epilepsy, bipolar disorder, trigeminal neuralgia, attention-deficit hyperactivity disorder, partial seizures, adjunctive therapy for partial, myoclonic, tonic-clonic seizures and schizophrenia, neuropathic pain, seizures, Tourette syndrome, Alzheimer's disease, autism, bipolar disorder and anxiety disorder, bipolar disorder, mania, phantom limb syndrome, complex regional pain syndrome, paroxysmal extreme pain disorder, neuromyotonia, intermittent explosive disorder, borderline personality disorder, myotonia congenita and post-traumatic stress disorder.
An alternate synthesis of enantiomerically pure levetiracetam (Keppra)
Mujahid,Mujumdar,Sasikumar,Kunte,Muthukrishnan
, p. 1512 - 1515 (2013/01/15)
A simple and efficient synthesis of levetiracetam has been achieved with high enantiopurity (>99%) starting from commercially available benzyl glycidyl ether. The method is amenable for industrial scale-up.
Asymmetric synthesis of the antiepileptic drug levetiracetam
Imahori, Tatsushi,Omoto, Keisuke,Hirose, Yumi,Takahata, Hiroki
experimental part, p. 1627 - 1632 (2009/07/17)
Palladium-catalyzed asymmetric synthesis of levetiracetam of antiepileptic drug was expediently accomplished.