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761404-23-3

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761404-23-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 761404-23-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,1,4,0 and 4 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 761404-23:
(8*7)+(7*6)+(6*1)+(5*4)+(4*0)+(3*4)+(2*2)+(1*3)=143
143 % 10 = 3
So 761404-23-3 is a valid CAS Registry Number.

761404-23-3Downstream Products

761404-23-3Relevant articles and documents

Synthesis and structural-activity relationships of 3-hydroxyquinazoline-2, 4-dione antibacterial agents

Tran, Tuan P.,Ellsworth, Edmund L.,Stier, Michael A.,Domagala, John M.,Hollis Showalter,Gracheck, Stephen J.,Shapiro, Martin A.,Joannides, Themis E.,Singh, Rajeshwar

, p. 4405 - 4409 (2007/10/03)

The synthesis and SAR of the 3-hydroxyquinazoline diones, a novel class of bacterial topoisomerase inhibitors, is reported. A series of 3-hydroxyquinazoline-2,4-diones was synthesized and evaluated for antibacterial activity. This series represents a novel addition to the DNA gyrase inhibitor class of antibacterials. Appropriate substitutions onto the core template yielded compounds with excellent potency against E. coli gyrase and significant in vitro Gram-negative and Gram-positive antibacterial activity.

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