101513-77-3 Usage
Description
3-Chloro-2,4,5-trifluorobenzoic acid is an organic compound characterized by its white to light yellow powder form. It is a synthetic intermediate with significant applications in the pharmaceutical and chemical industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
3-Chloro-2,4,5-trifluorobenzoic acid is used as a synthetic intermediate for the development of various pharmaceutical compounds. Its primary application is in the synthesis of 3-hydroxyquinazoline-2,4-diones, which are known for their antibacterial properties. These compounds can be utilized in the creation of new antibiotics to combat bacterial infections.
Used in Chemical Industry:
In the chemical industry, 3-Chloro-2,4,5-trifluorobenzoic acid serves as a crucial building block for the synthesis of other complex organic molecules. Its unique structure, featuring a chlorine atom and three fluorine atoms, allows for further functionalization and modification, making it a versatile component in the synthesis of various specialty chemicals and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 101513-77-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,5,1 and 3 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 101513-77:
(8*1)+(7*0)+(6*1)+(5*5)+(4*1)+(3*3)+(2*7)+(1*7)=73
73 % 10 = 3
So 101513-77-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H2ClF3O2/c8-4-5(10)2(7(12)13)1-3(9)6(4)11/h1H,(H,12,13)/p-1
101513-77-3Relevant articles and documents
Novel C-7 carbon substituted fourth generation fluoroquinolones targeting N. Gonorrhoeae infections
Betson, Mark,Bingham, Matilda,Doyle, Paul,Hallworth, Sebastian,Harvey, Rebecca,Huxley, Anthony,Kirk, Ralph,Moat, John,Nelson, Gary,Pesnot, Thomas,Tait, Michael
, (2020)
Delafloxacin, a fourth-generation anionic fluoroquinolone (FQ) was approved in 2019 for community acquired bacterial pneumonia (CARP). It has broad spectrum activity and an improved class-related toxicity profile. However, it has recently failed a Phase 3
Preparation method of 3-chloro-2,4,5-trifluorobenzoic acid
-
, (2019/12/29)
The invention discloses a preparation method of 3-chloro-2,4,5-trifluorobenzoic acid. The reaction equation of the method is shown in the description. The preparation method concretely comprises the following steps: preparing a compound of formula (1) fro
2,3,4,5-tetrahalogenobenzene derivatives
-
, (2008/06/13)
2,3,4,5-trihalogenobenzene derivatives of the formula STR1 in which R is --COOH, --COCl, --COF, --CN, --CONH2, --CH2 OH, --CH2 Cl, --CHCl2, --CCl3 or --CHO, R1 is H, Cl or F, and R2 is Cl or F, it only being possible for R1 or R2 to be F, and processes for their preparation starting from benzonitriles reacted with potassium fluoride. The novel compounds are intermediates for antibacterials such as quinolone carboxylic acids.