639007-38-8

Basic information

• Product Name: N-benzyl-2-(butane-1-sulfonyl)-acetamide
• Synonyms: N-benzyl-2-(butane-1-sulfonyl)-acetamide
• CAS NO: 639007-38-8
• Molecular Weight: 269.365
• Mol File: 639007-38-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyl-2-(butane-1-sulfonyl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-2-(butane-1-sulfonyl)-acetamide(639007-38-8)
• EPA Substance Registry System: N-benzyl-2-(butane-1-sulfonyl)-acetamide(639007-38-8)

Safety Data

• Hazardous Substances Data: 639007-38-8(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 2564-06-9 N-benzyl-2-chloroacetamide 
• 2386-54-1 1-butanesulfonic acid sodium salt 

Relevant articles and documents

Reaction of different α-sulfonyl acetamides with methyl acrylate

The base-induced tandem-coupling/cyclization reactions of various α-sulfonyl acetamide derivatives A with methyl acrylate differentiated between two different pathways to form α-sulfonyl analogs of glutarimides B and 2-hydroxycyclohexenecarboxylic acid derivatives C in different ratios. The reaction of α-sulfonyl acetamide dianion with methyl acrylate depended on three factors: the stability of the dianion, concentration of methyl acrylate and the structure of sufonyl and amide substituents. By changing the reaction conditions, we efficiently controlled the cycloaddition reaction to synthesize the desired product, each of which has potential biological activities. A ring closure mechanism is proposed for the reactions.