2386-54-1

Basic information

• Product Name: Sodium 1-butanesulfonate
• Synonyms: IPC-ALKS-4;BUTYLSULFONIC ACID SODIUM SALT;BUTANE 1-SULFONIC ACID SODIUM SALT;BUTANE-1-SULPHONIC ACID SODIUM SALT;sodium butane-1-sulphonate;1-BUTANESULFONIC ACID SODIUM SALT CONC., FOR IPC, 6 AMP.;1-BUTANESULFONIC ACID SODIUM SALT MONOHH YDRATE;1-BUTANESULFONIC ACID SODIUM
• CAS NO: 2386-54-1
• Molecular Formula: C₄H₉O₃S*Na
• Molecular Weight: 160.17
• EINECS: 219-201-1
• Product Categories: Analytical Chemistry;HPLC Ion-Pair Reagents for Basic Samples;Ion-Pair Reagents for HPLC;Building Blocks;Chemical Synthesis;Organic Building Blocks;Sulfonic/Sulfinic Acid Salts;Sulfur Compounds
• Mol File: 2386-54-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: >300 °C(lit.)
• Appearance: White to off-white/Crystalline Powder
• Density: 1.221g/cm3
• Storage Temp.: Store below +30°C.
• Solubility: H2O: 0.1 g/mL, clear to slightly hazy
• Water Solubility: soluble
• BRN: 3716662
• CAS DataBase Reference: Sodium 1-butanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: Sodium 1-butanesulfonate(2386-54-1)
• EPA Substance Registry System: Sodium 1-butanesulfonate(2386-54-1)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 37/39-26-36
• WGK Germany: 3
• F: 8-10-23
• TSCA: Yes
• Hazardous Substances Data: 2386-54-1(Hazardous Substances Data)

Usage

Description

Sodium 1-butanesulfonate, an anionic detergent, is a white to off-white crystalline powder. It is a versatile compound with various applications across different industries due to its unique chemical properties.

Uses

Used in Chemical Synthesis:
Sodium 1-butanesulfonate is used as a reagent in the Suzuki reaction, a widely employed method for the formation of carbon-carbon bonds, particularly in the synthesis of complex organic molecules.
Used in Analytical Chemistry:
Sodium 1-butanesulfonate is used as a mobile phase to separate eight selenium compounds, including selenite, selenate, selenocystine, selenourea, selenomethionine, selenoethionine, selenocystamine, and trimethylselenonium ion. This application is crucial for the accurate analysis and identification of these compounds in various samples.
Used in High Silicon Content SAPO4-5 Synthesis:
In the field of materials science, Sodium 1-butanesulfonate is utilized in the synthesis of high silicon content SAPO4-5, a type of molecular sieve with potential applications in catalysis and gas separation.
Used in Chromatography:
Sodium 1-butanesulfonate serves as an ion-associating reagent for high-performance liquid chromatography (HPLC) and reversed-phase chromatography. Its use in these techniques aids in the separation and analysis of various compounds, enhancing the efficiency and accuracy of the chromatographic processes.

Biochem/physiol Actions

Sodium 1-butanesulfonate can be used in the preparation of mobile phase for high performance liquid chromatography-inductively coupled plasma-mass spectrometry (HPLC-ICP-MS).

InChI:InChI=1/C4H10O3S/c1-2-3-4-8(5,6)7/h2-4H2,1H3,(H,5,6,7)/p-1

Upstream product

• 72500-12-0 Trimethylsilyl-1-butansulfonat 
• 109-69-3 n-Butyl chloride 
• 109-65-9 1-bromo-butane 
• 2386-60-9 perfluoro-1-butanesulfonyl fluoride 
• 542-69-8 1-iodo-butane 

Downstream Products

• 639007-38-8 N-benzyl-2-(butane-1-sulfonyl)-acetamide 
• 1293990-63-2 2-phenyl-9-tetradecyl-benzo[8,9]quinolizino[4,5,6,7-fed]phenanthridinylium butanesulfonate 
• 2386-60-9 perfluoro-1-butanesulfonyl fluoride 

Relevant articles and documents

Preparation of sodium sulfonates using by copper as catalyst

The sodium alkyl sulfonates were prepared by Strecker reaction. The synthesis of sodium chloroethyl sulfonate from dichloroethane and sodium sulfite with different catalysts, it was found that copper was an efficient catalyst with a yield (81%). The reaction conditions were also optimized to make the route more competitive and suitable for large-scale industrial production. Besides, some more sulfonates were also obtained with copper as catalyst via Strecker reaction.

Synthesis of Aromatic and Olefinic Sodium Sulfonates by Electrophilic Destannylation with Trimethylsilyl Chlorosulfonate

A mild and effective method for the preparation of a variety of aromatic, olefinic, and acetylenic sodium sulfonates is described.The reaction of trialkylaryl- (2a-k) and -heteroarylstannanes (4a-d), bis-(1-alkenyl)dibutylstannanes (6a-f), or trialkylakynylstannanes with trimethylsilyl chlorosulfonate (1) followed by hydrolysis with aqueous NaHCO3 provides the sodium sulfonates in an ipso-specific and in the case of vinylic stannanes stereospecific manner.A comparision of the reactivity of stannylated and silylated olefinic compounds 13 and 14 underlines the greater leaving ability of the stannyl moiety.The in situ preparation of the stannanes makes it possible to apply the synthetic method to natural products such as N-substituted apocodeine (17). - Key Words: Electrophilic aromatic substitution/ Electrophilic vinylic substitution/ Trialkylstannanes, application of/ Arylsulfonates, sodium salts of/ Vinylsulfonates, sodium salts of

Studies on Sulphochlorination of Paraffins. VIII. Studies on the Hydrolysis of Individual Alkane Sulphochlorides by Sodium Hydroxide

The hydrolysis of individual C1-C5 alkane sulphochlorides by sodium hydroxide in dioxane/water (1:1) was kinetically studied at 25 deg C by means of stopped-flow technique, measuring the change of electric conductivity.The rate constants were influenced by steric hindrance, but in all cases were higher than the rate constant for alkaline hydrolysis of benzene sulphochloride, which cannot react according to the elimination-addition (sulphene) mechanism.The reaction enthalpy of the alkaline hydrolysis of four individual alkane sulphochlorides was determined by a simple calorimetric apparatus; the average value amounts to ΔRH = -239 kJ mol-1.