63603-28-1

Basic information

• Product Name: Benzene, [(2-methoxy-2-phenylethyl)seleno]-
• CAS NO: 63603-28-1
• Molecular Formula: C15H16OSe
• Molecular Weight: 291.251
• Mol File: 63603-28-1.mol
• Article Data: 25

Chemical Properties

• CAS DataBase Reference: Benzene, [(2-methoxy-2-phenylethyl)seleno]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(2-methoxy-2-phenylethyl)seleno]-(63603-28-1)
• EPA Substance Registry System: Benzene, [(2-methoxy-2-phenylethyl)seleno]-(63603-28-1)

Safety Data

• Hazardous Substances Data: 63603-28-1(Hazardous Substances Data)

Upstream product

• 1666-13-3 diphenyl diselenide 
• 108415-83-4 (E)-β-styryl phenyl selenone 
• 108415-85-6 (Z)-β-styryl phenyl selenone 
• 67545-97-5 n-octyl phenyl selenoxide 
• 71766-38-6 Dodecyl phenyl selenoxide 
• 65275-53-8 β-Phenethyl-phenyl-selenoxid 
• 65275-52-7 Isobutyl(phenyl)selenoxid 
• 65275-51-6 n-propyl phenyl selenoxide 
• 34837-55-3 Phenylselenyl bromide 
• 5707-04-0 Phenylselenyl chloride 
• 915127-49-0 N-phenylselenosaccharin 
• 100-42-5 styrene 
• 67-56-1 methanol 
• 51558-95-3 1-phenyl-2-(phenylselanyl)ethanol 

Downstream Products

• 101-48-4 phenylacetaldehyde dimethyl acetal 
• 98-86-2 acetophenone 
• 35050-01-2 α-(phenylseleno)acetophenone 
• 1074-11-9 1-(1,2-dichloroethyl)benzene 
• 3898-26-8 2-chloro-1-phenyl-1-methoxyethane 
• 4747-13-1 α-methoxystyrene 
• 108415-87-8 2-methoxy-2-phenyl-1-(phenylselenonyl)ethane 
• 113674-98-9 1-methoxy-1-phenyl-2-phenylseleninylethane 
• 116117-96-5 1-phenyl-1-methoxy-2-phenylselenenyl ethane dichloride 
• 55163-72-9 (RS)-(2-ethoxy-2-methoxy-ethyl)-benzene 

Relevant articles and documents

Iodosobenzene-Mediated Three-Component Selenofunctionalization of Olefins

A three-component reaction of olefin, diselenide and water, alcohols, phenol, carboxylic acid, or amine by a commercially available hypervalent iodine(III) reagent, PhIO, was developed. This method provides access to a wide range of vicinally functionalized selenoderivatives under ambient conditions with mostly excellent yields and high diastereoselectivity. The developed reaction displays high levels of functional group compatibility and is suitable for the late-stage functionalization of styrene-functionalized biomolecules. Preliminary investigations on the mechanism of the reaction are also presented.

A novel and efficient alkoxylselenenylation of alkenes

A novel and efficient alkoxylselenenylation from alkenes, diselenides, and alcohols mediated by iodine is developed, with which a series of β-alkoxy selenides are synthesized. In this procedure, firstly, I2 reacts with diselenide to form in situ the active electrophilic selenium species RSeI, then following an electrophilic addition of it to alkenes provides β-alkoxy selenides with high regioselectivity and in good yields. This new method for achieving β-alkoxy selenides has some advantages over other methods such as using available and cheap iodine as the oxidizing species at room temperature, which makes this reaction has milder reaction conditions and simpler procedure.

Electrochemical Aminoselenation and Oxyselenation of Styrenes with Hydrogen Evolution

The use of additive-free conditions is an ideal approach to prepare organoselenium reagents from readily available unsaturated substrates. Thus, we report the electro-induced aminoselenation and oxyselenation of styrenes without any acids or oxidants as additives. This transformation is compatible with various functional groups, which leads to vicinal difunctionalized organoselenium compounds. Our strategy improves the potential of this protocol for use in the pharmaceutical industry. Based upon the preliminary mechanism studies, we propose two possible pathways.