619-45-4Relevant articles and documents
Photosensitive self-assembled monolayers on gold: Photochemistry of surface-confined aryl azide and cyclopentadienylmanganese tricarbonyl
Wollman, Eric W.,Kang, Doris,Frisbie, C. Daniel,Lorkovic, Ivan M.,Wrighton, Mark S.
, p. 4395 - 4404 (1994)
Photosensitive self-assembled monolayers (SAMs) are prepared by the spontaneous reaction of di-11-(4-azidobenzoate)-1-undecyl disulfide, I, or 11-mercaptoundecylcyclopentadienylmanganese tricarbonyl, II, with polycrystalline Au. SAMs of I are photosensitive by virtue of a pendant aryl azide moiety (λmax = 270 nm, log ε = 4.2) which undergoes photoreaction with secondary amines to form Au-confined derivatives of 3-H azepine and hydrazine, while Au-II SAMs undergo photosubstitution of phosphine for CO. Au-I SAMs irradiated in the presence of various secondary amines were characterized by reflection absorption infrared spectroscopy (RAIRS), XPS, and cyclic voltammetry, and showed persistent attachment of approximately one monolayer of amine. Infrared spectroscopy was used to establish that primary photoproducts obtained upon irradiation of Au-I SAMs in diethylamine are nearly identical to primary photoproducts obtained upon irradiating an analog of I, methyl 4-azidobenzoate, in diethylamine solution. XPS analysis of Au-I SAMs before and after irradiation in the presence of secondary amines confirms loss of N2 from the Au-I SAM and incorporation of one nitrogen atom per surface-confined molecule. Most definitively, cyclic voltammetry of Au-I after irradiation in the presence of 2-ferrocenylethyl-2′,2′,2′-trifluoroethylamine, III, showed 3.3 × 10-10 mol cm-2 of surface-confined ferrocene. Positive ion SIMS spectra of Au-II irradiated in the presence of PPh2Et, PPh2(n-Pr), PPh2(CH2)11Fc, X, Fc = ferrocenyl, or PPh2(CH2)2(CF2)5CF 3, XI, show that introduction of the phosphine onto the surface occurs upon near-UV irradiation. Importantly, the surface photochemistry of I and II allows the high lateral resolution patterning of Au surfaces and Au microstructures with a variety of molecular reagents. SIMS maps for vinyl ferrocenium (m/z 212) or F- (m/z 19) of flat Au-II substrates irradiated through a Cr-on-glass mask in the presence of X or XI demonstrate photochemical patterning at a lateral resolution of 2H5OH)2NH.
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Schwartz,Paruta
, p. 252,253-255 (1976)
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Carboxyl Methyltransferase Catalysed Formation of Mono- and Dimethyl Esters under Aqueous Conditions: Application in Cascade Biocatalysis
Ashbrook, Chloe,Carnell, Andrew J.,Goulding, Ellie,Hatton, Harry,Johnson, James R.,Kershaw, Neil M.,McCue, Hannah V.,Rigden, Daniel J.,Ward, Lucy C.
supporting information, (2022/02/21)
Carboxyl methyltransferase (CMT) enzymes catalyse the biomethylation of carboxylic acids under aqueous conditions and have potential for use in synthetic enzyme cascades. Herein we report that the enzyme FtpM from Aspergillus fumigatus can methylate a broad range of aromatic mono- and dicarboxylic acids in good to excellent conversions. The enzyme shows high regioselectivity on its natural substrate fumaryl-l-tyrosine, trans, trans-muconic acid and a number of the dicarboxylic acids tested. Dicarboxylic acids are generally better substrates than monocarboxylic acids, although some substituents are able to compensate for the absence of a second acid group. For dicarboxylic acids, the second methylation shows strong pH dependency with an optimum at pH 5.5–6. Potential for application in industrial biotechnology was demonstrated in a cascade for the production of a bioplastics precursor (FDME) from bioderived 5-hydroxymethylfurfural (HMF).
METHOD OF PREPARING(3R,5R)-7-(2-(4-FLUOROPHENYL)-5-ISOPROPYL-3-PHENYL-4-((4-HYDROXYMETHYLPHENYLAMINO)CARBONYL)-PYRROL-1-YL)-3,5-DIHYDROXY-HEPTANOIC ACID HEMI CALCIUM SALT, AND METHOD OF PREPARING INTERMEDIATES USED THEREIN
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Paragraph 0079-0082, (2021/02/05)
The present invention provides a method for preparing (3R,5R)-7-(2-(4-flurophenyl)-5-isopropyl-3-phenyl-4-((4-hydroxymethylphenylamino)carbonyl)-pyrrole-1-yl)-3,5-dihydroxy heptanoic acid hemicalcium salt. The preparation method of the present invention is performed in a convergent synthesis manner in which main structural moieties of a (3R,5R)-7-(2-(4-flurophenyl)-5-isopropyl-3-phenyl-4-((4-hydroxymethylphenylamino)carbonyl)-pyrrole-1-yl)-3,5-dihydroxy heptanoic acid hemicalcium salt are independently synthesized, and then coupled. Accordingly, related substances can be easily controlled and preparing time can be reduced, thus improving the productivity of a compound, and the yield of a final compound can also be increased.
An amino-functionalized three-dimensional cadmium metal–organic framework: Synthesis, characterization and excellent fluorescence sensing of Fe3+
Han, Youjie,Tian, Ye,Yin, Jifa,Zhu, Hongmei
, p. 845 - 849 (2021/06/06)
An amino-functionalized three-dimensional cadmium metal–organic framework, [Cd1.5(L)(DMF)]·2H2O (complex 1) L = H3TTCA-NH2 = 2′-amino-[1,1′:3′,1″-terphenyl]-4,4″,5′-tricarboxylic acid), is successfully synthesized under solvothermal conditions and structurally characterized. Interestingly, as a transition metal organic framework, the cadmium metal–organic framework exhibits favorable luminescence properties. In addition, the cadmium metal–organic framework reveals excellent selective and sensitive fluorescence sensing for the recognition of Fe3+ with high quenching efficiency (Ksv = 3.340 × 103 M?1), demonstrating that the cadmium metal–organic framework can be used as a potential sensor for Fe3+.