532931-48-9

Basic information

• Product Name: Benzoic acid, 4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-(diphenylphosphino)-, methyl ester
• CAS NO: 532931-48-9
• Molecular Formula: C25H20NO6P
• Molecular Weight: 461.411
• Mol File: 532931-48-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-(diphenylphosphino)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-(diphenylphosphino)-, methyl ester(532931-48-9)
• EPA Substance Registry System: Benzoic acid, 4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-(diphenylphosphino)-, methyl ester(532931-48-9)

Safety Data

• Hazardous Substances Data: 532931-48-9(Hazardous Substances Data)

Upstream product

• 299173-24-3 [3-iodo-4-(methoxycarbonyl)]benzoic acid 
• 60728-41-8 1-methyl-2-aminoterephthalate 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 361154-31-6 3-(diphenylphosphino)-4-(methoxycarbonyl)benzoic acid 
• 105832-38-0 O-(N-succinimidyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate 

Downstream Products

• 1262279-73-1 methyl 2(diphenylphosphino)-4-(2-(2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoyloxy)ethoxy)ethylcarbamoyl)benzoate 
• 628708-15-6 2-diphenylphosphanyl-N-(2-{2-[2-(4-(pyren-1-yl)butyrylamino)ethoxy]ethoxy}ethyl)terephthalamic acid methyl ester 
• 628708-16-7 2-diphenylphosphanyl-N-(ethoxycarbonylmethyl)terephthalamic acid methyl ester 
• 868394-26-7 N-{2-[2-(2-amino-ethoxy)-ethoxy]-ethyl}-2-diphenylphosphanyl-terephthalamic acid methyl ester 

Relevant articles and documents

MASSIVE PARALLEL METHOD FOR DECODING DNA AND RNA

This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotide analogues which comprise unique labels attached to the nucleotide analogue through a cleavable linker, and a cleavable chemical group to cap the —OH group at the 3′-position of the deoxyribose.

Conversion of Aryl Azides to O-Alkyl Imidates via Modified Staudinger Ligation

(Equation presented) o-Carboalkoxy triarylphosphines are shown to react with aryl azides to provide Staudinger ligation products bearing O-alkyl imidate linkages. This is in contrast to alkyl azides whose ligation to o-carboalkoxy triarylphosphines has been reported to yield amide-linked materials. This extension of the Staudinger ligation for coupling of abiotic reagents under biocompatible conditions highlights the utility of commercially available triarylphosphines through which suitable linkers can be attached via an ester moiety.