52924-55-7

Basic information

• Product Name: Benzaldehyde, 5-bromo-2,3-dihydroxy-
• CAS NO: 52924-55-7
• Molecular Formula: C7H5BrO3
• Molecular Weight: 217.019
• Mol File: 52924-55-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 5-bromo-2,3-dihydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 5-bromo-2,3-dihydroxy-(52924-55-7)
• EPA Substance Registry System: Benzaldehyde, 5-bromo-2,3-dihydroxy-(52924-55-7)

Safety Data

• Hazardous Substances Data: 52924-55-7(Hazardous Substances Data)

Upstream product

• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 
• 5034-74-2 5-bromo-3-methoxysalicylaldehyde 

Downstream Products

• 1372864-95-3 5-(5-bromo-2,3-dihydroxybenzylidene)-3-(2-ethylbutyl)thiazolidine-2,4-dione 
• 72744-55-9 6-bromo-1,3-benzodioxole-4-carboxaldehyde 
• 866535-39-9 3,4-Bis-methoxymethoxy-5-[(Z)-3-methyl-4-(tetrahydro-pyran-2-yloxy)-but-2-enyl]-benzaldehyde 
• 866535-41-3 3,4-Dihydroxy-5-((Z)-4-hydroxy-3-methyl-but-2-enyl)-benzaldehyde 
• 866535-35-5 5-formyl-2,3-bis(methoxymethyloxy)benzyl alcohol 
• 866535-37-7 3-bromomethyl-4,5-bis-methoxymethoxy-benzaldehyde 
• 866535-76-4 (5-bromo-2,3-bis-methoxymethoxy-phenyl)-methanol 
• 866535-74-2 5-bromo-2,3-bis-methoxymethoxy-benzaldehyde 

Relevant articles and documents

Imidazo ring PAR4 antagonist and medical applications thereof

The invention relates to an imidazo ring compound represented by formula (I) or formula (II), or a pharmaceutically acceptable salt or ester or solvate thereof. The compound disclosed by the inventioncan be used for preparing medicines for preventing or treating thromboembolic diseases.

Method for preparing 5-halogen-2,3-dihydroxy benzaldehyde

The invention discloses a method for preparing 5-halogen-2,3-dihydroxy benzaldehyde. The method comprises the following steps: enabling 5-halogen-2-hydroxyl-3-methoxybenzaldehyde to generate ether bond cracking reaction at a temperature from -20 DEG C to

Development of a scalable process for CI-1034, an endothelin antagonist

A concise, convergent multikilogram synthesis of CI-1034 (1), a potent endothelin receptor antagonist, is described. A 15-step preparation from commercially available o-vanillin and benzenesulfonyl chloride employs a remarkably robust Suzuki coupling between a boronic acid and an aromatic sulfonate ester as the key synthetic step. A scalable route capable of producing multikilogram quantities of CI-1034 with no chromatographic steps is described in this contribution. Improvements to the process included using a 4-fluorobenzenesulfonate ester as a suitable substitute for the triflate group in the Suzuki reaction and the use of MgCl2 as a substitute for TiCl4 in a Dieckmann condensation to provide the benzothiazine dioxide core.