3685-84-5 Usage
Description
Meclofenoxate hydrochloride is a white solid that serves as a cerebral stimulant and a plant growth regulator. It is known for its ability to promote the metabolism of the brain and act as an Acetylcholine precursor, which is essential for cognitive functions.
Uses
Used in Pharmaceutical Industry:
Meclofenoxate hydrochloride is used as a cerebral stimulant for addressing memory decline through aging, dementia, Alzheimer's, brain damage or injuries, and alleviating the symptoms and effects of alcohol or drug abuse. It helps improve cognitive functions by acting as an Acetylcholine precursor, which is crucial for memory and learning.
Used in Agriculture:
Meclofenoxate hydrochloride is used as a plant growth regulator, enhancing the growth and development of plants by modulating their metabolic processes and promoting overall plant health.
Pharmacological action
Meclofenoxate hydrochloride(MecloCl) [CAS,NO:51-68-3], an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA), has been shown to improve memory, have a mentally stimulating effect, and improve general cognition.
Meclofenoxate hydrochloride is a psychostimulant in the nootropic agent group available in capsule and tablet formulations approved for traumatic cataphora, alcoholic poisoning, anoxia neonatorum, and children's enuresis in China. Although these 2 generic formulations are marketed in China, information regarding their pharmacokinetics and bioequivalence in humans has not been published. Meclofenoxate hydrochloride appears to increase the consolidation of new information into long-term memory. Meclofenoxate does not affect other aspects of remembering. Meclofenoxate is found that significantly more of the subjects receiving meclofenoxate reportes an increased level of mental alertness.
Safety Profile
Poison by intravenous route.Moderately toxic by ingestion and intraperitoneal routes.When heated to decomposition it emits very toxic fumes ofCl??, NOx, and HCl.
Check Digit Verification of cas no
The CAS Registry Mumber 3685-84-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,8 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3685-84:
(6*3)+(5*6)+(4*8)+(3*5)+(2*8)+(1*4)=115
115 % 10 = 5
So 3685-84-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H16ClNO3.ClH/c1-14(2)7-8-16-12(15)9-17-11-5-3-10(13)4-6-11;/h3-6H,7-9H2,1-2H3;1H
3685-84-5Relevant articles and documents
A meclofenoxate hydrochloride preparation method
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Paragraph 0035-0040; 0041; 0044, (2019/03/25)
The invention discloses a meclofenoxate hydrochloride of the preparation method, comprises the following steps: (A) will acid with thionyl chloride in chlorobenzene acyl chloride reaction, to obtain the chlorophenoxy acetyl chloride; (B) step (A) to get chlorophenoxy acetyl chloride and dimethyl amino ethanol by condensation reaction to obtain the meclofenoxate free alkali; (C) step (B) to obtain the free base of the salt-forming acid salt, thermal insulation and filtering to obtain the hydrochloride. The invention easy availability of raw materials, the reaction temperature is low, the operation is convenient, the crude product of high purity, stable quality, the present invention provides a more easy operation, more environmentally friendly, more economic meclofenoxate hydrochloride synthetic pathway.
Preparation and preliminary pharmacological study of the dimethylamino-ethyl esters of various acids acting as plant growth regulators.
THUILLIER,RUMPF,THUILLIER
, p. 2081 - 2083 (2007/11/05)
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