2498-25-1 Usage
Uses
1. As a reagent in organic synthesis, particularly for the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
2. As a building block for the preparation of various organic compounds, including amines, amides, and esters.
3. In the synthesis of chiral compounds, as it can act as a chiral auxiliary or a chiral ligand in asymmetric catalysis.
4. As a starting material for the preparation of other functionalized alcohols and amines.
5. In the synthesis of biologically active compounds, such as alkaloids, peptides, and nucleosides.
Safety and handling:
1. 2-(Dimethylamino)-ethanol hydrochloride should be handled in a well-ventilated area, as it can release irritating vapors.
2. It is recommended to wear appropriate personal protective equipment (PPE), such as gloves, safety goggles, and a lab coat, when handling this compound.
3. In case of contact with skin or eyes, immediately rinse with plenty of water and seek medical attention if necessary.
4. Dispose of the compound according to local regulations and guidelines for hazardous materials.
Check Digit Verification of cas no
The CAS Registry Mumber 2498-25-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,9 and 8 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2498-25:
(6*2)+(5*4)+(4*9)+(3*8)+(2*2)+(1*5)=101
101 % 10 = 1
So 2498-25-1 is a valid CAS Registry Number.
InChI:InChI=1/C4H11NO.ClH/c1-5(2)3-4-6;/h6H,3-4H2,1-2H3;1H
2498-25-1Relevant articles and documents
End-to-end continuous flow synthesis and purification of diphenhydramine hydrochloride featuring atom economy, in-line separation, and flow of molten ammonium salts
Snead, David R.,Jamison, Timothy F.
, p. 2822 - 2827 (2013/07/27)
A continuous end-to-end synthesis and purification of diphenhydramine hydrochloride featuring atom economy and waste minimization is described. Combining a 1:1 molar ratio of the two starting material streams (chlorodiphenylmethane and N,N-dimethylaminoethanol) in the absence of additional solvent at high temperature gives the target compound directly as a molten salt (ionic liquid above 168 °C) in high yield. This represents the first example of continuous active pharmaceutical ingredient (API) production in this manner. Six of the twelve principles of green chemistry as defined by the American Chemical Society are achieved, most prominently waste minimization and atom economy.
Degradation of gabexate mesilate by sodium bisulfite
Asahara,Yamada,Yoshida,Hirose
, p. 1595 - 1599 (2007/10/02)
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Stability of solid dosage forms. I. Hydrolysis of meclofenoxate hydrochloride in the solid state
Yoshioka,Shibazaki,Ejima
, p. 3734 - 3741 (2007/10/02)
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