268212-48-2

Basic information

• Product Name: 3-amino-5-(5-phenyl-1H-pyrrol-2-yl)-1H-pyrazole-4-carboxamide
• CAS NO: 268212-48-2
• Molecular Weight: 267.29
• Mol File: 268212-48-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-amino-5-(5-phenyl-1H-pyrrol-2-yl)-1H-pyrazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-5-(5-phenyl-1H-pyrrol-2-yl)-1H-pyrazole-4-carboxamide(268212-48-2)
• EPA Substance Registry System: 3-amino-5-(5-phenyl-1H-pyrrol-2-yl)-1H-pyrazole-4-carboxamide(268212-48-2)

Safety Data

• Hazardous Substances Data: 268212-48-2(Hazardous Substances Data)

Downstream Products

• 23868-34-0 tetrabutylammonium bifluoride 

Relevant articles and documents

A highly selective fluorescent sensor for fluoride anion based on pyrazole derivative: Naked eye "no-yes" detection

A new pyrazole-based fluorescent sensor, 5-amino-3-(5-phenyl-1H-pyrrol-2- yl)-1H-pyrazole-4-carboxamide (compound 1), was studied for fluoride anion (F-) detection in organic or water-containing solution. This compound displayed both changes in UV-vis absorption and fluorescence emission spectra upon addition of F-. With increasing of F-, blue emission intensity increases drastically and reaches saturation with 607-fold enhancement at 424 nm. The results indicate that compound 1 has highly selectivity for fluoride detection over other anions, such as Cl-, Br-, I-, HSO4-, H2PO4 - and AcO- in DMSO or aqueous DMSO solutions. 1H NMR titration and other experiments confirm that the sensing process is mainly from the deprotonation of the pyrazole-NH in compound 1.