23868-34-0 Usage
Description
Tetrabutylammonium hydrogen difluoride, also known as Bu4NHF2, is a colorless, hygroscopic solid that is highly soluble in water and polar organic solvents. It is a versatile reagent in organic chemistry, known for its ability to promote various types of fluorination reactions. Its unique properties make it a valuable compound in the synthesis of a wide range of organic molecules.
Uses
Used in Chemical Synthesis:
Tetrabutylammonium hydrogen difluoride is used as a reactant for nucleophilic fluorination, ring-opening fluorination reactions, and substitution reactions. It serves as a source of the nucleophilic difluoride anion (HF2-), which can selectively introduce fluorine atoms into organic molecules, making it a valuable tool in the synthesis of fluorinated compounds.
Used in the Electronics Industry:
Tetrabutylammonium hydrogen difluoride is used as an etchant for silica films. This application is particularly important in the manufacturing of semiconductor devices, where precise etching of silica layers is crucial for the performance and reliability of the final product.
Used in the Pharmaceutical Industry:
Tetrabutylammonium hydrogen difluoride can be employed in the synthesis of various pharmaceutical compounds, particularly those containing fluorine atoms. The unique reactivity of the difluoride anion allows for the selective introduction of fluorine into complex molecular structures, which can significantly impact the pharmacological properties of the resulting compounds.
Used in the Research and Development of New Materials:
Due to its ability to promote a variety of fluorination reactions, Tetrabutylammonium hydrogen difluoride is also used in the research and development of new materials with potential applications in various industries, such as aerospace, automotive, and energy sectors. The introduction of fluorine atoms can significantly alter the properties of these materials, making them more suitable for specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 23868-34-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,8,6 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 23868-34:
(7*2)+(6*3)+(5*8)+(4*6)+(3*8)+(2*3)+(1*4)=130
130 % 10 = 0
So 23868-34-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H36N.2FH/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;;/h5-16H2,1-4H3;2*1H/q+1;;/p-1
23868-34-0Relevant articles and documents
A highly selective fluorescent sensor for fluoride anion based on pyrazole derivative: Naked eye "no-yes" detection
Yang, Zhipei,Zhang, Kai,Gong, Fangbin,Li, Shayu,Chen, Jun,Ma, Jin Shi,Sobenina, Lyubov N.,Mikhaleva, Albina I.,Trofimov, Boris A.,Yang, Guoqiang
body text, p. 29 - 34 (2011/10/03)
A new pyrazole-based fluorescent sensor, 5-amino-3-(5-phenyl-1H-pyrrol-2- yl)-1H-pyrazole-4-carboxamide (compound 1), was studied for fluoride anion (F-) detection in organic or water-containing solution. This compound displayed both changes in UV-vis absorption and fluorescence emission spectra upon addition of F-. With increasing of F-, blue emission intensity increases drastically and reaches saturation with 607-fold enhancement at 424 nm. The results indicate that compound 1 has highly selectivity for fluoride detection over other anions, such as Cl-, Br-, I-, HSO4-, H2PO4 - and AcO- in DMSO or aqueous DMSO solutions. 1H NMR titration and other experiments confirm that the sensing process is mainly from the deprotonation of the pyrazole-NH in compound 1.
