18793-44-7

Basic information

• Product Name: Acetamide, N-[(1E)-2-phenylethenyl]-
• CAS NO: 18793-44-7
• Molecular Formula: C10H11NO
• Molecular Weight: 161.203
• Mol File: 18793-44-7.mol
• Article Data: 37

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[(1E)-2-phenylethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[(1E)-2-phenylethenyl]-(18793-44-7)
• EPA Substance Registry System: Acetamide, N-[(1E)-2-phenylethenyl]-(18793-44-7)

Safety Data

• Hazardous Substances Data: 18793-44-7(Hazardous Substances Data)

Upstream product

• 2887-98-1 benzalacetone oxime 
• 5202-78-8 acetylaminoethylene 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 60-35-5 acetamide 
• 122-78-1 phenylacetaldehyde 
• 1722-84-5 (E)-N-styrylacetamide 
• 55065-02-6 N-acetamido cinnamic acid 
• 18756-03-1 (E)-(2-azidovinyl)benzene 
• 108-24-7 acetic anhydride 
• 20544-50-7 cis-2-phenyl-1-azidoethene 
• 588-72-7 [(E)-2-bromoethenyl]benzene 
• 877-95-2 methyl-N-(benzyl-methyl)-formamide 
• 2901-75-9 (R,S)-N-acetyl phenylalanine 
• 6926-44-9 phenethyl azide 

Downstream Products

• 1722-84-5 (Z)-N-styrylacetamide 
• 73885-72-0 trans-N-methoxycarbonyl-2-phenylethenylamine 
• 118653-24-0 methyl(E)-N-formyl-N-(2-phenylethenyl)acetamide 
• 90289-81-9 Demethoxytuberin 
• 118653-35-3 (S)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N-((E)-styryl)-propionamide 
• 118653-26-2 [(S)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-propionyl]-((E)-styryl)-carbamic acid methyl ester 
• 1384452-16-7 N-(1-((3-(benzyloxy)propyl)(diphenyl)silyl)-2-phenylethyl)acetamide 
• 1722-84-5 (E)-N-styrylacetamide 
• 436157-42-5 dimethyl (1-acetamido-2-phenylvinyl)phosphonate 
• 3969-09-3 2-methyl-5-phenyl-1,3-oxazole 
• 97305-95-8 (Z)-N-benzyl-N-styrylacetamide 
• 21156-62-7 N-acetylphenylalanine methyl ester 
• 2901-75-9 (R,S)-N-acetyl phenylalanine 
• 176433-57-1 2-chloro-5-phenyl-3-pyridine carboxaldehyde 

Relevant articles and documents

Dehydrative Beckmann rearrangement and the following cascade reactions

The Beckmann rearrangement has been predominantly studied for the synthesis of amide and lactam. By strategically using the in situ generated Appel's salt or Mitsunobu's zwitterionic adduct as the dehydrating agent, a series of Beckmann rearrangement and following cascade reactions have been developed herein. The protocol allows the conversion of various ketoximes into amide, thioamide, tetrazole and imide products in modular procedures. The generality and tolerance of functionalities of this method have been demonstrated.

Photoredox/Cobalt Dual-Catalyzed Decarboxylative Elimination of Carboxylic Acids: Development and Mechanistic Insight

Recently, dual-catalytic strategies towards the decarboxylative elimination of carboxylic acids have gained attention. Our lab previously reported a photoredox/cobaloxime dual catalytic method that allows the synthesis of enamides and enecarbamates directly from N-acyl amino acids and avoids the use of any stoichiometric reagents. Further development, detailed herein, has improved upon this transformation's utility and further experimentation has provided new insights into the reaction mechanism. These new developments and insights are anticipated to aid in the expansion of photoredox/cobalt dual-catalytic systems.

An Electrochemical Beckmann Rearrangement: Traditional Reaction via Modern Radical Mechanism

Abstract: Electrosynthesis as a potential means of introducing heteroatoms into the carbon framework is rarely studied. Herein, the electrochemical Beckmann rearrangement, i. e. the direct electrolysis of ketoximes to amides, is presented for the first time. Using a constant current as the driving force, the reaction can be easily carried out under neutral conditions at room temperature. Based on a series of mechanistic studies, a novel radical Beckmann rearrangement mechanism is proposed. This electrochemical Beckmann rearrangement does not follow the trans-migration rule of the classical Beckmann rearrangement.