1807-97-2Relevant articles and documents
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Abramovitch et al.
, p. 2030 (1962)
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Martin et al.
, p. 327,329 (1974)
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Visible-Light-Induced C2 Alkylation of Pyridine N-Oxides
Zhang, Wen-Man,Dai, Jian-Jun,Xu, Jun,Xu, Hua-Jian
supporting information, p. 2059 - 2066 (2017/02/26)
A photoredox catalytic method has been developed for the direct C2 alkylation of pyridine N-oxides. This reaction is compatible with a range of synthetically relevant functional groups for providing efficient synthesis of a variety of C2-alkylated pyridine N-oxides under mild conditions. Mechanistic studies are consistent with the generation of a radical intermediate along the reaction pathway.
Functionalization of Pyridine via Direct Metallation
Verbeek, Jacob,George, Albert V. E.,Jong, Robertus L. P. de,Brandsma, Lambert
, p. 257 - 258 (2007/10/02)
The isolation of mixtures of 2-, 3-, and 4-deuteriopyridine, 2-, 3-, and 4-trimethylsilylpyridine, or 2-, 3-, and 4-methylthiopyridine indicates successful metallation of pyridine with a 1:1 mixture of BuLi-ButOK in tetrahydrofuran-hexane at -100 deg C.
