PYRIDINE-2-D1

Base Information

• Chemical Name: PYRIDINE-2-D1
• CAS No.: 1807-97-2
• Molecular Formula: C5H4 D N
• Molecular Weight: 80.0935
• Mol file: 1807-97-2.mol

Synonyms:Pyridine-2-d1

Chemical Property of PYRIDINE-2-D1

Chemical Property:

• PSA: 12.89000
• LogP: 1.08160

Purity/Quality:

99% ^*data from raw suppliers

Pyridine-2-d1 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Pyridine-2-d1 (CAS# 1807-97-2) is a useful isotopically labeled research compound.

Technology Process of PYRIDINE-2-D1

There total 11 articles about PYRIDINE-2-D1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyridine (110-86-1) → 2-deuterio-pyridine (1807-97-2) + 3-deuterio-pyridine (3748-86-5) + 4-deuterio-pyridine (10259-15-1)

Guidance literature:

With n-butyllithium; deuteromethanol; potassium tert-butylate; In tetrahydrofuran; hexane; at -105 ℃; Product distribution; var. time, solvent;

DOI:10.1039/c39840000257

Reference yield:

pyridine (110-86-1) → 2-deuterio-pyridine (1807-97-2) + 3-deuterio-pyridine (3748-86-5) + 4-deuterio-pyridine (10259-15-1) + C5H5(2)H2N + C5H5(2)H2N

Guidance literature:

With lithium aluminium deuteride; water; at 90 ℃; for 168h; Product distribution; Mechanism; other temperatures, other times;

DOI:10.1021/jo00059a041

Reference yield:

2-bromo-pyridine (109-04-6) → 2-deuterio-pyridine (1807-97-2)

Guidance literature:

With deuteriosulfuric acid; water-d2; zinc;

DOI:10.1063/1.1739983

upstream raw materials:

2-bromo-pyridine

pyridine

deuteromethanol

C₈H₅F₆NO

Downstream raw materials:

2-(benzofuran-2-yl)pyridine

pyridine

Refernces

• 1、 Forsyth, David A.,Hanley, John A.. "Conformationally Dependent Intrinsic and Equilibrium Isotope Effects in N-Methylpiperidine". . p. 7930 - 7932. Retrieved 1987.
• 2、 Ling, Xiang,Xu, Yangsen,Wu, Shaoping,Liu, Mofan,Yang, Peng,Qiu, Chuntian,Zhang, Guoqiang,Zhou, Hongwei,Su, Chenliang. "A visible-light-photocatalytic water-splitting strategy for sustainable hydrogenation/deuteration of aryl chlorides". . p. 386 - 392. Retrieved 2020/02/25.
• 3、 Tanner, Dennis D.,Yang, Chi-Ming. "On the Structure and Mechanism of Formation of the Lansbury Reagent, Lithium Tetrakis(N-dihydropyridyl)aluminate". . p. 1840 - 1846. Retrieved 2007/10/02.