148989-73-5

Basic information

• Product Name: 7-(2,5-Dihydroxy-3,4,6-triMethylphenyl)-7-phenylheptanoic acid
• Synonyms: 7-(2,5-Dihydroxy-3,4,6-triMethylphenyl)-7-phenylheptanoic acid
• CAS NO: 148989-73-5
• Molecular Formula: C₂₂H₂₈O₄
• Molecular Weight: 356.45532
• Mol File: 148989-73-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 586.5±50.0 °C(Predicted)
• Appearance: /
• Density: 1.153±0.06 g/cm3(Predicted)
• PKA: 4.77±0.10(Predicted)
• CAS DataBase Reference: 7-(2,5-Dihydroxy-3,4,6-triMethylphenyl)-7-phenylheptanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(2,5-Dihydroxy-3,4,6-triMethylphenyl)-7-phenylheptanoic acid(148989-73-5)
• EPA Substance Registry System: 7-(2,5-Dihydroxy-3,4,6-triMethylphenyl)-7-phenylheptanoic acid(148989-73-5)

Safety Data

• Hazardous Substances Data: 148989-73-5(Hazardous Substances Data)

Upstream product

• 112665-42-6 7-hydroxy-7-phenyl-heptanoic acid ethyl ester 
• 112665-41-5 ethyl 7-oxo-7-phenylheptanoate 
• 700-13-0 Trimethylhydroquinone 
• 103187-18-4 7-hydroxy-7-phenylheptanoic acid 
• 33018-91-6 7-ethoxy-7-oxoheptanoic acid 
• 14794-32-2 ethyl 6-(chloroformyl)hexanoate 

Downstream Products

• 112665-40-4 p-nitrophenyl 7-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoate 
• 103186-19-2 (-)-AA 2414 
• 103187-09-3 (+)-AA 2414 
• 112665-43-7 seratrodast 

Relevant articles and documents

Indium-catalyzed synthesis of keto esters from cyclic 1,3-diketones and alcohols and application to the synthesis of seratrodast

Esterification reactions from cyclic 1,3-diketones and alcohols are carried out in the presence of several Lewis acids. In particular, indium(III) triflate, In(OTf)3, iron(III) triflate, Fe-(OTf)3, copper(II) triflate, Cu(OTf)2, and silver(I) triflate, AgOTf, show high catalytic activities. These reactions proceed through the carbon-carbon bond cleavage by a retro-aldol reaction and were found to be highly regioselective even in the presence of other functional groups. This type of reaction can also be applied to the preparation of the keto esters during the synthesis of seratrodast, which is an antiasthmatic and eicosanoid antagonist.