1390626-97-7Relevant articles and documents
A novel and highly efficient protocol for the synthesis of chalcone based 1,2-diazepine and 1,2-oxazepine derivatives
Babu, B. Venkata,Ahmed, Naseem
experimental part, p. 1155 - 1177 (2012/07/27)
A novel and highly efficient protocol is described for the synthesis of chalcone based 1,2-diazepine and 1,2-oxazepine derivatives. Under neat condition, the mixing and grinding of 1,5-diketones and hydrazine gave the cyclocondensation products in quantitative yields within 10-20 min at room temperature. Similarly, novel chalcone based 1,2-oxazepines were synthesized in excellent yields (85-88%) in 2-3 h at refluxed by the condensation of 1,5-diktones and hydroxylamine hydrochloride in water-ethanolic base.