1245-00-7 Usage
Description
(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester is an alkaloid derived from the Vinca species, specifically found in V. rosea L. It forms colorless crystals from methanol (MeOH) and exhibits levorotation with a specific rotation of [α]26D 58° (MeOH). When crystallized from dimethyl carbonate (Me2CO), it forms crystals containing solvent of crystallization, with a melting point of 181°C. The ultraviolet spectrum in MeOH has absorption maxima at 226, 282, and 290 nm. This alkaloid contains a primary alcoholic group and an imino group, yielding various derivatives such as the hemisulphate (m.p. 239-241°C, dec.), the picrate (m.p. 226-8°C, dec.), and the O-acetate (m.p. 198°C; [α]26D 26°, MeOH).
Uses
1. Used in Pharmaceutical Industry:
(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester is used as a pharmaceutical compound for its potential therapeutic applications. The presence of a primary alcoholic group and an imino group allows for further chemical modifications and the development of new drugs with improved properties.
2. Used in Chemical Research:
This alkaloid is used as a research compound in the field of organic chemistry, particularly for studying the structure, properties, and potential applications of alkaloids derived from the Vinca species.
3. Used in Drug Development:
(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester serves as a starting material for the synthesis of new drugs, taking advantage of its unique structural features and functional groups.
4. Used in Analytical Chemistry:
The alkaloid can be employed in analytical chemistry for the development of new methods and techniques for the identification, quantification, and analysis of similar compounds in various samples, including biological and environmental matrices.
5. Used in Material Science:
The unique structural features of (16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester may also find applications in material science, potentially leading to the development of new materials with specific properties and applications.
References
Svoboda et al., J. Pharm. Sci., 50,409 (1961) Kutney, Brown., Tetrahedron Lett., 1815 (1963)
Check Digit Verification of cas no
The CAS Registry Mumber 1245-00-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,4 and 5 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1245-00:
(6*1)+(5*2)+(4*4)+(3*5)+(2*0)+(1*0)=47
47 % 10 = 7
So 1245-00-7 is a valid CAS Registry Number.
