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(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester

Base Information Edit
  • Chemical Name:(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester
  • CAS No.:1245-00-7
  • Molecular Formula:C21H26N2O3
  • Molecular Weight:354.449
  • Hs Code.:
  • Mol file:1245-00-7.mol
(16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester

Synonyms:17,18-Secoyohimban-16-carboxylicacid, 18,19-didehydro-17-hydroxy-, methyl ester, (16R)- (8CI);Corynan-16-carboxylic acid, 18,19-didehydro-17-hydroxy-, methyl ester, (16R)-;Sitsirikine (7CI); Sitsirikin

Suppliers and Price of (16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Crysdot
  • Sitsirikine 95+%
  • 5mg
  • $ 922.00
  • Arctom
  • 16R-sitsirikine ≥98%
  • 5mg
  • $ 593.00
Total 7 raw suppliers
Chemical Property of (16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester Edit
Chemical Property:
  • Melting Point:206 - 209 °C 
  • Boiling Point:545.4±50.0 °C(Predicted) 
  • PKA:14.30±0.10(Predicted) 
  • PSA:65.56000 
  • Density:1.25±0.1 g/cm3(Predicted) 
  • LogP:2.60860 
Purity/Quality:

HPLC≥98% *data from raw suppliers

Sitsirikine 95+% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Description One of the numerous alkaloids isolated from Vinca species, this base occurs in V. rosea L. and forms colourless crystals from MeOH. It is laevorotatory with[α]26D - 58° (MeOH) and when crystallized from Me2CO forms crystals containing solvent of crystallization, m.p. 181°C. The ultraviolet spectrum in MeOH has absorption maxima at 226, 282 and 290 mf.1. The alkaloid contains a primary alcoholic group and an imino group and yields the hemisulphate, m.p. 239- 241°C (dec.); the picrate, m.p. 226-8°C (dec.) and the O-acetate, m.p. 198°C;[α]26D- 26° (MeOH).
Technology Process of (16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester

There total 1 articles about (16R)-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
Strictosidin 2, β-Glucosidase, NaBH3CN;
DOI:10.1016/S0040-4039(01)86223-7
Guidance literature:
With hydrogen; palladium on activated charcoal; In methanol; for 0.166667h; Ambient temperature;
Downstream raw materials:

19,20-dihydroisositsirikine

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