1031-15-8 Usage
Description
Methyl triphenyl phosphonium chloride is a versatile organophosphorus compound with the chemical formula (C6H5)3PCH3. It is known for its unique properties and wide range of applications across various industries.
Uses
1. Synthetic Chemistry:
Methyl triphenyl phosphonium chloride is used as a phase transfer catalyst in synthetic chemistry. It facilitates the transfer of reactants between different phases, such as between an aqueous and an organic phase, thereby enhancing the efficiency of chemical reactions.
2. Polymerization:
In the field of polymer science, it acts as a catalyst for regio-controlled ring-opening polymerization of substituted epoxides. This application is crucial for the synthesis of polymers with specific structures and properties.
3. Corrosion Control:
Methyl triphenyl phosphonium chloride is utilized for controlling the corrosion of iron. It helps in preventing the degradation of iron and steel structures, which is essential for maintaining the integrity and longevity of various industrial equipment and infrastructure.
4. Intramolecular Nitrone Cycloaddition:
It acts as a reactant in intramolecular nitrone cycloaddition, a chemical reaction that is used to form complex molecular structures. This reaction is particularly useful in the synthesis of pharmaceutical compounds and other specialty chemicals.
5. Anticancer Applications:
Methyl triphenyl phosphonium chloride is used for neoplasm inhibition through its antimitochondrial effect. It has the potential to disrupt the function of mitochondria in cancer cells, thereby inhibiting their growth and proliferation.
Check Digit Verification of cas no
The CAS Registry Mumber 1031-15-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,3 and 1 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1031-15:
(6*1)+(5*0)+(4*3)+(3*1)+(2*1)+(1*5)=28
28 % 10 = 8
So 1031-15-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H18P.ClH/c1-20(17-11-5-2-6-12-17,18-13-7-3-8-14-18)19-15-9-4-10-16-19;/h2-16H,1H3;1H/q+1;/p-1
1031-15-8Relevant articles and documents
Long sought synthesis of quaternary phosphonium salts from phosphine oxides: Inverse reactivity approach
Vetter, Anna C.,Nikitin, Kirill,Gilheany, Declan G.
, p. 5843 - 5846 (2018)
Quaternary phosphonium salts (QPS), a key class of organophosphorus compounds, have previously only been available by routes involving nucleophilic phosphorus. We report the realisation of the opposite approach to QPS utilising phosphine oxides as the electrophilic partner and Grignard reagents as nucleophiles. The process is enabled through the crucial intermediacy of the derived halophosphonium salts. The route does not suffer from the slow kinetics and limited availability of many parent phosphines and a broad range of QPS were prepared in excellent yields.
Exploring an Umpolung strategy for quaternization of phosphorus
Vetter, Anna C.,Nikitin, Kirill,Gilheany, Declan G.
, p. 339 - 342 (2019)
We propose a new, potentially widely-applicable, Umpolung approach for the synthesis of quaternary phosphonium salts R3PR1 X (X = Cl, Br) from phosphine oxides R3PO. The new organic group R1 is introduced via nucleophilic attack on an intermediate halophosphonium salt using a Grignard reagent R1MgX and replaces the traditional phosphine quaternization approach. Consequently, the new method does not suffer from the limited availability of many parent phosphines and is much faster than standard quaternization.
Practical synthesis of phosphonium salts with orthoformates and their application as flame retardants in polycarbonate
Jiang, Pingkai,Li, Tao,Xu, Chencong,Zhang, Yong Jian
, (2020/03/23)
An efficient and practical approach to phosphonium salts has been developed. By the reaction of phosphines and different acid sources with orthoformates in one-step operation, the process allowed rapid access to phosphonium salts with diverse counterions in high yield after the purification by recrystallization. The flame retardant performance in PC has also been examined by blending several phosphonium salts to PC respectively. Phosphonium phosphates showed excellent flame retardancy in PC with only 2 phr blending.
