1020719-89-4 Usage
Description
Sulfathiazole-d4 is an isotopically labeled antibacterial drug derived from sulfathiazole. It is a pale yellow crystalline solid and is used for various applications in different industries due to its unique properties.
Uses
Used in Pharmaceutical Industry:
Sulfathiazole-d4 is used as a research compound for studying the metabolic pathways and pharmacokinetics of sulfonamide drugs. Its isotopically labeled nature allows for easier tracking and analysis of the drug's distribution, metabolism, and excretion in the body.
Used in Microbiology:
Sulfathiazole-d4 is used as a tracer in microbiological research to investigate the mechanisms of bacterial resistance to sulfonamide antibiotics. This helps in understanding the development of antibiotic resistance and aids in the development of new strategies to combat it.
Used in Environmental Studies:
Sulfathiazole-d4 can be employed as a tracer in environmental studies to monitor the presence and distribution of sulfonamide drugs in water bodies and soil. This helps in assessing the impact of these drugs on the environment and developing methods to reduce their pollution.
Used in Veterinary Medicine:
Sulfathiazole-d4 is used as a diagnostic tool in veterinary medicine to detect the presence of sulfonamide residues in animal tissues. This is important for ensuring the safety of animal-derived food products and preventing the transmission of antibiotic-resistant bacteria to humans.
Check Digit Verification of cas no
The CAS Registry Mumber 1020719-89-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,0,7,1 and 9 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1020719-89:
(9*1)+(8*0)+(7*2)+(6*0)+(5*7)+(4*1)+(3*9)+(2*8)+(1*9)=114
114 % 10 = 4
So 1020719-89-4 is a valid CAS Registry Number.
1020719-89-4Relevant articles and documents
Stable isotope deuterium labeled sulfanilamide drug and preparation method thereof
-
, (2018/04/26)
The invention belongs to the technical field of chemical synthesis, and specifically relates to a stable isotope deuterium labeled sulfanilamide drug and a preparation method thereof. The preparationmethod comprises the following steps: (1) subjecting benzene-d6 (I) to a nitratlon reaction so as to prepare deuterium labeled nitrobenzene-d5 (II); (2) reducing nitro of the deuterium labeled nitrobenzene-d5 (II) so as to prepare deuterium labeled aniline-d5 (III); (3) under the conditions of anhydrous sodium acetate and glacial acetic acid, subjecting the deuterium labeled aniline-d5 (III) and acetic anhydride to a reaction so as to prepare deuterium labeled N-acetanilide-d5 (IV); (4) subjecting the deuterium labeled N-acetanilide-d5 (IV) and chlorosulfonic acid to a reaction so as to prepare deuterium labeled 1-chlorosulfonyl-4-acetamidobenzene-d4 (V); and (5) allowing R to substitute chlorine of the deuterium labeled 1-chlorosulfonyl-4-acetamidobenzene-d4 (V), and carrying out hydrolysis so as to prepare an isotope deuterium labeled sulfanilamide drug (VII). The preparation method provided by the invention has the advantages of simple reaction conditions, short reaction time, highconversion efficiency, strong economy, and applicability to mass synthesis.
