1020719-82-7 Usage
Description
Sulfamethazine-D4 is an isotopically labeled derivative of the antibacterial drug Sulfamethazine, characterized by its pale yellow crystalline appearance. It is primarily used in the field of pharmaceuticals and medical research, offering valuable insights into the mechanisms of action and metabolic pathways of the parent compound, Sulfamethazine.
Uses
Used in Pharmaceutical Industry:
Sulfamethazine-D4 is used as a research tool for studying the pharmacokinetics, metabolism, and mechanisms of action of Sulfamethazine. Its isotopically labeled nature allows for easier tracking and analysis of the drug's behavior within biological systems.
Used in Medical Research:
In the field of medical research, Sulfamethazine-D4 serves as a valuable compound for investigating the efficacy and safety of Sulfamethazine in treating bacterial infections. It can be employed in various experimental setups, including in vitro and in vivo studies, to better understand the drug's interactions with bacterial cells and its potential side effects.
Used in Antimicrobial Applications:
Sulfamethazine-D4 is used as an antibacterial agent, particularly effective against a wide range of bacterial infections. Its isotopically labeled form provides a means to study the drug's activity and resistance development in bacteria, which can be crucial for the development of new and improved antimicrobial therapies.
Used in Drug Development:
Sulfamethazine-D4 can be utilized in the development of new drugs with similar or improved properties to Sulfamethazine. By understanding the structure-activity relationships and metabolic pathways of Sulfamethazine-D4, researchers can design and synthesize novel compounds with enhanced antibacterial activity and reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 1020719-82-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,0,7,1 and 9 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1020719-82:
(9*1)+(8*0)+(7*2)+(6*0)+(5*7)+(4*1)+(3*9)+(2*8)+(1*2)=107
107 % 10 = 7
So 1020719-82-7 is a valid CAS Registry Number.
1020719-82-7Relevant articles and documents
Stable isotope deuterium labeled sulfanilamide drug and preparation method thereof
-
, (2018/04/26)
The invention belongs to the technical field of chemical synthesis, and specifically relates to a stable isotope deuterium labeled sulfanilamide drug and a preparation method thereof. The preparationmethod comprises the following steps: (1) subjecting benzene-d6 (I) to a nitratlon reaction so as to prepare deuterium labeled nitrobenzene-d5 (II); (2) reducing nitro of the deuterium labeled nitrobenzene-d5 (II) so as to prepare deuterium labeled aniline-d5 (III); (3) under the conditions of anhydrous sodium acetate and glacial acetic acid, subjecting the deuterium labeled aniline-d5 (III) and acetic anhydride to a reaction so as to prepare deuterium labeled N-acetanilide-d5 (IV); (4) subjecting the deuterium labeled N-acetanilide-d5 (IV) and chlorosulfonic acid to a reaction so as to prepare deuterium labeled 1-chlorosulfonyl-4-acetamidobenzene-d4 (V); and (5) allowing R to substitute chlorine of the deuterium labeled 1-chlorosulfonyl-4-acetamidobenzene-d4 (V), and carrying out hydrolysis so as to prepare an isotope deuterium labeled sulfanilamide drug (VII). The preparation method provided by the invention has the advantages of simple reaction conditions, short reaction time, highconversion efficiency, strong economy, and applicability to mass synthesis.
