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CAS No.: | 52-66-4 |
---|---|
Name: | DL-PENICILLAMINE |
Article Data: | 21 |
Molecular Structure: | |
Formula: | C5H11 N O2 S |
Molecular Weight: | 149.214 |
Synonyms: | DL-Valine,3-mercapto-; Valine, 3-mercapto-, DL- (8CI); (?à)-Penicillamine; 2-Amino-3-mercapto-3-methylbutyricacid; Cysteine, 3,3-dimethyl-; DL-3-Mercaptovaline; DL-Penicillamine; DL-b-Mercaptovaline; DMC; NSC 22880;NSC 44656; b,b-Dimethylcysteine; b-Mercaptovaline; b-Thiovaline |
Density: | 1.204g/cm3 |
Melting Point: |
204-208 °C(lit.) |
Boiling Point: | 251.8°Cat760mmHg |
Flash Point: | 106.1°C |
Solubility: | Soluble in ethanol, hot water and sodium hydroxide. |
Hazard Symbols: | Xn |
Risk Codes: | R22; |
Safety: | Poison by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx. |
PSA: | 102.12000 |
LogP: | 0.80700 |
Conditions | Yield |
---|---|
With hydrogenchloride |
Conditions | Yield |
---|---|
Behandeln des Reaktionsprodukts mit Essigsaeure und wss.HCl; |
formate
2-amino-2-carboxy-1,1-dimethyl-ethylsulfanyl
A
DL-Penicillamin
B
formate radical
Conditions | Yield |
---|---|
In various solvent(s) at 23℃; Equilibrium constant; pH 6; |
2-amino-2-carboxy-1,1-dimethyl-ethylsulfanyl
D,L-dithiothreitol
A
DL-Penicillamin
Conditions | Yield |
---|---|
In water at 23℃; Thermodynamic data; pH=6.0; phosphate buffer; ΔGo; |
Conditions | Yield |
---|---|
In acetonitrile at 37℃; for 72h; Mechanism; Rate constant; pH=2.5; |
A
DL-Penicillamin
B
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Conditions | Yield |
---|---|
In water at 25℃; for 5h; Rate constant; Equilibrium constant; pH 7.0; |
Conditions | Yield |
---|---|
In water at 25℃; for 5h; Rate constant; Equilibrium constant; pH 7.0; |
DL-Penicillamin
Conditions | Yield |
---|---|
With hydrogen bromide | |
With hydrogenchloride |
DL-Penicillamin
Conditions | Yield |
---|---|
With hydrogenchloride; aluminium |
DL-Penicillamin
Conditions | Yield |
---|---|
With ammonia; sodium | |
With hydrogen bromide |
IUPAC Name: 2-Amino-3-methyl-3-sulfanylbutanoic acid
The MF of Dl-penicillamine (CAS NO.52-66-4) is C5H11NO2S.
The MW of Dl-penicillamine (CAS NO.52-66-4) is 149.21.
Synonyms of Dl-penicillamine (CAS NO.52-66-4): (2S)-2-Amino-3-methyl-3-sulfanylbutansaure ; 3-Sulfanyl-D-valine ; b,b-Dimethylcysteine ; b-Thiovaline ; Distamine
Product Categories: Amino Acids;Antibiotics;Analytical Chemistry;Biochemistry;Ligands for Pharmaceutical Research;non-Proteinorganic Amino Acids;Radiopharmaceutical Chemistry
Index of Refraction: 1.527
Appearance: white powder
EINECS: 200-147-2
Density: 1.204 g/ml
Flash Point: 106.1 °C
Boiling Point: 251.8 °C
Melting Point: 4-8 °C
storage temp: 2-8 °C
Merck: 14,7088
BRN: 2039817
Dl-penicillamine (CAS NO.52-66-4) is used in chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.
1. | pic-esc 100 mg/L | APMBAY Applied Microbiology. 12 (1964),234. | ||
2. | orl-rat LD50:365 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 22 (1972),1434. | ||
3. | ipr-mus LD50:358 mg/kg | TOLED5 Toxicology Letters. 26 (1985),95. |
Poison by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.Safety information of Dl-penicillamine (CAS NO.52-66-4):
Hazard Codes Xn
Risk Statements
R36/37/38:Irritating to eyes, respiratory system and skin.
R40:Limited evidence of a carcinogenic effect.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S22:Do not breathe dust.
WGK Germany 3
RTECS YV9445000