N-ETHYLPROPIONAMIDE

Base Information

• Chemical Name: N-ETHYLPROPIONAMIDE
• CAS No.: 5129-72-6
• Molecular Formula: C5H11NO
• Molecular Weight: 101.148
• Hs Code.: 2924199090
• Mol file: 5129-72-6.mol

Synonyms:ethylpropionamide;N-Ethylpropanamide;Propionamide, N-ethyl-;N-PROPIONYLETHYLAMINE;N-ETHYLPROPIONAMIDE;N-ETHYLPROPIONAMIDE 99+%

Chemical Property of N-ETHYLPROPIONAMIDE

Chemical Property:

• Refractive Index: 1.4340-1.4370
• Boiling Point: 116 °C / 25mmHg
• Flash Point: 108.3oC
• PSA: 29.10000
• Density: 0,91 g/cm3
• LogP: 0.92340

Purity/Quality:

98% ^*data from raw suppliers

N-Ethylpropionamide ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-ETHYLPROPIONAMIDE

There total 5 articles about N-ETHYLPROPIONAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

pentan-3-one (96-22-0) → 3-pentanone oxime (1188-11-0) + N-ethylpropionamide (5129-72-6)

Guidance literature:

With acetylhydroxamic acid; sulfuric acid; In acetonitrile; for 10.5h; Reflux;

DOI:10.1016/j.tetlet.2011.09.019

Reference yield: 27.9%

propionic acid (802294-64-0,79-09-4) + Trimethylenediamine (109-76-2,54018-94-9) → 2-methylpyrimidine (5053-43-0) + N-ethylpropionamide (5129-72-6) + N-propyl propanamide (3217-86-5) + 2-ethyl-pyrimidine (60544-11-8)

Guidance literature:

aluminum oxide; palladium/alumina; for 33h; 1) 290 deg C, 2) 320 deg C;

DOI:10.1021/jo00036a031

Reference yield: 16.0%

→ Methyl formate (107-31-3) + N-ethylpropionamide (5129-72-6)

Guidance literature:

upstream raw materials:

diethyl ether

chloroacetylene

diethylamine

propionic acid

Downstream raw materials:

ethylpropylamine

ethyl-propionyl-carbamic acid benzyl ester

ethyl-(1-trimethylsilanyloxy-propyl)-carbamic acid benzyl ester

2-chloro-5-(1,1-dimethylethyl)-1,3-dinitrobenzene

Refernces

• 1、 Madabhushi, Sridhar,Chinthala, Narsaiah,Vangipuram, Venkata Sairam,Godala, Kondal Reddy,Jillella, Raveendra,Mallu, Kishore Kumar Reddy,Beeram, China Ramanaiah. "Microwave-assisted efficient one-step synthesis of amides from ketones and benzoxazoles from (2-hydroxyaryl) ketones with acetohydroxamic acid using sulfuric acid as the catalyst". experimental part. p. 6103 - 6107. Retrieved 2011/11/30.
• 2、 -. "Process for the preparation of formamides". . . Retrieved 2008/06/13.