Ethion

Base Information

• Chemical Name: Ethion
• CAS No.: 563-12-2
• Deprecated CAS: 12738-47-5
• Molecular Formula: C9H22 O4 P2 S4
• Molecular Weight: 384.483
• European Community (EC) Number: 209-242-3
• ICSC Number: 0888
• UN Number: 3018,2783
• UNII: 2TI07NO12Y
• DSSTox Substance ID: DTXSID2024086
• Nikkaji Number: J3.297B
• Wikipedia: Ethion
• Wikidata: Q414724
• NCI Thesaurus Code: C163655
• Metabolomics Workbench ID: 55957
• ChEMBL ID: CHEMBL1713417
• Mol file: 563-12-2.mol

Synonyms:diethion;ethion;Ethopaz;Niagara 1240;Nialate;RP 8167

Chemical Property of Ethion

Chemical Property:

• Appearance/Colour: yellow to beige crystalline powder
• Vapor Pressure: 2.78E-06mmHg at 25°C
• Melting Point: 3oC
• Refractive Index: nD20 1.5490
• Boiling Point: 125(0.0013kPa)
• Flash Point: 196.5oC
• PSA: 171.32000
• Density: 1.22
• LogP: 6.30650
• Storage Temp.: 0-6°C
• Water Solubility.: 2 mg l-1 (25 °C)
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 12
• Exact Mass: 383.98761787
• Heavy Atom Count: 19
• Complexity: 279
• Transport DOT Label: Poison

Purity/Quality:

Ethion reference material ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Cholinesterase inhibitor, use may be restricted. TLV: 0.4 mg/m³.
• Hazard Codes: T,N
• Statements: 21-25-50/53
• Safety Statements: 25-36/37-45-60-61-23

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Pesticides -> Organophosphate Insecticides
• Canonical SMILES: CCOP(=S)(OCC)SCSP(=S)(OCC)OCC
• Inhalation Risk: Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying.
• Effects of Short Term Exposure: The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. Cholinesterase inhibition. Exposure could cause unconsciousness and death. The effects may be delayed. Medical observation is indicated.
• Effects of Long Term Exposure: Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.
• Uses: It is used as a pesticide. Insecticide; acaricide. Nonsystemic insecticide and acaricide used on apples. Ethion is used to control mites and sucking insects, larval Lepidoptera and soil pests in a wide range of crops and in turf. An additional use is as an ectoparasiticide to control cattle ticks.

Technology Process of Ethion

There total 7 articles about Ethion which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + bis(diethoxyphosphoryl)disulphide (2901-90-8) → Ethion (563-12-2)

Guidance literature:

In diethyl ether; at -10 ℃;

Reference yield: 68.0%

dichloromethane (75-09-2) + diethyl dithiophosphate ammonium salt (1068-22-0) → chlormephos (24934-91-6) + Ethion (563-12-2)

Guidance literature:

In N,N-dimethyl-formamide; at 49 ℃; for 22h; Heating;

Reference yield:

potassium O,O-diethyldithiophosphate (3454-66-8) → Ethion (563-12-2)

Guidance literature:

With ethanol;

upstream raw materials:

formaldehyd

O,O-Diethyl hydrogen phosphorodithioate

potassium O,O-diethyldithiophosphate

1,1-dibromomethane

Refernces

• 1、 Hudson, Harry R.,Lynch, Vincent P.,Pianka, Max,Soares, Vera M.. "PRODUCTS OF THE ALKALINE HYDROLYSIS OF S-CHLOROMETHYL AND S-(N-ETHOXYCARBONYL-N-METHYLCARBAMOYLMETHYL) O,O-DIETHYLPHOPHORODITHIOATE". . p. 277 - 281. Retrieved 2007/10/02.
• 2、 Brand, William W.,Carr, Michael C.. "CHLOROMETHYLATION AT SULFUR WITH METHYLENE CHLORIDE. PREPARATION OF S-CHLOROMETHYL O,O-DIETHYL PHOSPHORODITHIOATE.". . p. 323 - 324. Retrieved 2007/10/02.