(chlorodifluoroMethyl)triMethylsilane

Base Information

• Chemical Name: (chlorodifluoroMethyl)triMethylsilane
• CAS No.: 115262-00-5
• Molecular Formula: C4H9ClF2Si
• Molecular Weight: 158.651
• Hs Code.: 29319090
• Mol file: 115262-00-5.mol

Synonyms:(Chlorodifluoromethyl)trimethylsilane;

Chemical Property of (chlorodifluoroMethyl)triMethylsilane

Chemical Property:

• Boiling Point: 90.0±40.0 °C(Predicted)
• PSA: 0.00000
• Density: 1.039±0.06 g/cm3(Predicted)
• LogP: 3.11530

Purity/Quality:

99% ^*data from raw suppliers

(Chloro-difluoro-methyl)-trimethyl-silane 96% ^*data from reagent suppliers

Safty Information:

• Statements: 11
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (Chlorodifluoromethyl)trimethylsilane, is one of the partially fluorinated compounds, which are often used for diverse applications in materials science, agrochemistry, and the pharmaceutical industry.

Technology Process of (chlorodifluoroMethyl)triMethylsilane

There total 6 articles about (chlorodifluoroMethyl)triMethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

[bromo(difluoro)methyl]-trimethyl-silane (115262-01-6) → [chloro(difluoro)methyl]trimethylsilane (115262-00-5)

Guidance literature:

With tetrabutyl-ammonium chloride; silver(I) chloride; In benzonitrile; at 20 ℃; for 6h; Time; Temperature; Reagent/catalyst; Solvent;

DOI:10.3762/bjoc.10.32

Reference yield: 20.0%

chloro-trimethyl-silane (75-77-4) + halon-1211 (353-59-3) → [chloro(difluoro)methyl]trimethylsilane (115262-00-5)

Guidance literature:

With hexaethylphosphoric triamide; In various solvent(s); at -78 - 20 ℃;

DOI:10.1016/0022-328X(90)80061-4

Reference yield:

chloro-trimethyl-silane (75-77-4) + halon-1211 (353-59-3) → bromodifluoromethane (1511-62-2) + Chlorodifluoromethane (75-45-6) + trimethylsilyl fluoride (420-56-4) + [bromo(difluoro)methyl]-trimethyl-silane (115262-01-6) + [chloro(difluoro)methyl]trimethylsilane (115262-00-5)

Guidance literature:

With 1-methyl-pyrrolidin-2-one; aluminium; Mechanism; Product distribution; Ambient temperature; various reactant ratio, other temperature, ultrasound promotion;

DOI:10.1021/ja962990n

upstream raw materials:

chloro-trimethyl-silane

halon-1211

dibromodifluoromethane

[bromo(difluoro)methyl]-trimethyl-silane

Downstream raw materials:

trimethylsilyl fluoride

trimethyl(difluoromethyl)silane

bis(trimethylsilyl)difluoromethane

1,2-bis(trimethylsilyl)-1,1,2,2-tetrafluoroethane

Refernces

• 1、 Fedorov, Oleg V.,Kosobokov, Mikhail D.,Levin, Vitalij V.,Struchkova, Marina I.,Dilman, Alexander D.. "Halogenative difluorohomologation of ketones". . p. 5870 - 5876. Retrieved 2015/06/16.
• 2、 Tsymbal, Artem V.,Kosobokov, Mikhail D.,Levin, Vitalij V.,Struchkova, Marina I.,Dilman, Alexander D.. "Nucleophilic bromodifluoromethylation of iminium ions". . p. 7831 - 7835. Retrieved 2015/03/18.