Benzaldehyde N,N-dimethylhydrazone

Base Information

• Chemical Name: Benzaldehyde N,N-dimethylhydrazone
• CAS No.: 1075-70-3
• Molecular Formula: C9H12 N2
• Molecular Weight: 148.208
• Hs Code.: 2928000090
• NSC Number: 516742
• DSSTox Substance ID: DTXSID60430460
• Mol file: 1075-70-3.mol

Synonyms:Benzaldehyde N,N-dimethylhydrazone;1075-70-3;2-benzylidene-1,1-dimethylhydrazine;N-[(E)-benzylideneamino]-N-methylmethanamine;(2E)-1,1-dimethyl-2-(phenylmethylidene)hydrazine;NSC516742;SCHEMBL9023270;DTXSID60430460;Benzaldehyde,2,2-dimethylhydrazone;benzal-dehyde N,N-dimethylhydrazone;BAA07570;AKOS006241285;NSC-516742;N-(benzylideneamino)-N-methylmethanamine;AS-62440;1,1-DIMETHYL-2-(PHENYLMETHYLIDENE)HYDRAZINE

Chemical Property of Benzaldehyde N,N-dimethylhydrazone

Chemical Property:

• Vapor Pressure: 0.019mmHg at 25°C
• Boiling Point: 252.7°Cat760mmHg
• Flash Point: 106.6°C
• PSA: 15.60000
• Density: 0.91g/cm³
• LogP: 1.58210
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 148.100048391
• Heavy Atom Count: 11
• Complexity: 124

Purity/Quality:

99.5% ^*data from raw suppliers

2-Benzylidene-1,1-dimethylhydrazine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)N=CC1=CC=CC=C1
• Isomeric SMILES: CN(C)/N=C/C1=CC=CC=C1

Technology Process of Benzaldehyde N,N-dimethylhydrazone

There total 32 articles about Benzaldehyde N,N-dimethylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N,N-Dimethylhydrazine (57-14-7) + benzyl azide (622-79-7) → benzaldehyde N,N-dimethylhydrazone (1075-70-3)

Guidance literature:

iron(III) chloride; In acetonitrile; for 8h; Heating;

DOI:10.1021/jo000708w

Reference yield: 99.0%

benzaldehyde (100-52-7) + N,N-Dimethylhydrazine (57-14-7) → benzaldehyde N,N-dimethylhydrazone (1075-70-3)

Guidance literature:

With magnesium sulfate; In dichloromethane; at 20 ℃; for 20h;

DOI:10.1080/00397910600616776

Reference yield: 90.0%

(E)-1,1-dimethyl-2-(2-methylallylidene)hydrazine (66064-57-1) + [4-(benzylideneamino)phenyl]methanol (783-08-4) → (+/-)-(2S*,4S*)-4-[(2,2-dimethylhydrazono)methyl]-6-methoxy-4-methyl-2-phenyl-1,2,3,4-tetrahydroquinoline + benzaldehyde N,N-dimethylhydrazone (1075-70-3)

Guidance literature:

With indium(III) chloride; In acetonitrile; at 20 ℃; for 2h; diastereoselective reaction;

DOI:10.1002/chem.201103562

upstream raw materials:

benzaldehyde

N,N-Dimethylhydrazine

benzyl azide

benzoic acid

Downstream raw materials:

benzaldehyde, hydrazone

benzamide dimethylhydrazone

Phenyl-2,7-octadienylketon-dimethylhydrazon

N-[2-(Dimethyl-hydrazono)-2-phenyl-acetyl]-methanesulfonamide

Refernces

• 1、 Susinskis, Igors,Mekss, Peteris,Hmelnickis, Juris. "Method development for the determination of 1,1-dimethylhydrazine by the high-performance liquid chromatography–mass spectrometry technique". . p. 352 - 359. Retrieved 2018.
• 2、 Pendrak, Israil,Wittrock, Robert,Kingsbury, William D.. "Synthesis and Anti-HSV Activity of Methylenedioxy Mappicine Ketone Analogs". . p. 2912 - 2915. Retrieved 1995.
• 3、 Rej, Supriya,Chatani, Naoto. "Transient imine as a directing group for the metal-free o-C-H borylation of benzaldehydes". supporting information. p. 2920 - 2929. Retrieved 2021/03/01.
• 4、 Janhsen, Benjamin,Studer, Armido. "Perfluoroalkylation of Aryl-N,N-dimethyl Hydrazones Using Hypervalent Iodine(III) Reagents or Perfluoroalkyl Iodides". . p. 11703 - 11710. Retrieved 2017/11/24.