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Grayanotoxin iii 6,14-diacetate

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Name

Grayanotoxin iii 6,14-diacetate

EINECS N/A
CAS No. 30460-34-5 Density 1.3g/cm3
PSA 133.52000 LogP 1.30990
Solubility N/A Melting Point N/A
Formula C24H38 O8 Boiling Point 565.5°Cat760mmHg
Molecular Weight 454.561 Flash Point 184.8°C
Transport Information N/A Appearance N/A
Safety A poison by intraperitoneal and intravenous route. When heated to decomposition it emits acrid smoke and irritating vapors. Risk Codes N/A
Molecular Structure Molecular Structure of 30460-34-5 ((14R)-Grayanotoxane-3β,5,6β,10,14,16-hexol 6,14-diacetate) Hazard Symbols A poison.
Synonyms

7,9a-Methano-9aH-cyclopenta[b]heptalene,grayanotoxane-3,5,6,10,14,16-hexol deriv.; 6-O-Acetylgrayanotoxin I;Grayanotoxin III 6,14-diacetate; Rhodojaponin IV

 

Grayanotoxin iii 6,14-diacetate Chemical Properties

IUPAC Name: (2S,3aS,4R,4aR,7R,8R,9aS,11R,11aR,12R)-7,9a-Methano-9aH-cyclopenta(b)heptalene-2,4,8,11,11a,12(1H)-hexol, dodecahydro-1,1,4,8-tetramethyl-, 6,12-diacetate
Molecular Formula: C24H38O8
Molecular Weight: 454.62g/mol
Density: 1.3g/cm3
Boiling Point: 565.5°C at 760mmHg
Flash Point: 184.8°C
Freely Rotating Bonds: 8
Polar Surface Area: 89.52 Å2
Index of Refraction: 1.573
Molar Refractivity: 114.76 cm3
Molar Volume: 347.9 cm3
Polarizability: 45.49 ×10-24 cm3
Surface Tension: 58.3 dyne/cm 
Enthalpy of Vaporization: 97.58 kJ/mol
Vapour Pressure: 3.82E-15 mmHg at 25°C 
The Cas Register Number of Grayanotoxin iii 6,14-diacetate is 30460-34-5.The chemical synonyms of Grayanotoxin iii 6,14-diacetate (CAS NO.30460-34-5) are Rhodojaponin IV ; 6-Acetyl-grayanotoxin I ; 6-O-Acetyl grayanotoxin 1 ; Grayanotoxin III 6,14-diacetate ; LS-90765 ; 7,9a-Methano-9aH-cyclopenta(b)heptalene-2,4,8,11,11a,12(1H)-hexol, dodecahydro-1,1,4,8-tetramethyl-, 6,12-diacetate, (2S,3aS,4R,4aR,7R,8R,9aS,11R,11aR,12R)- .Product categories  of Grayanotoxin iii 6,14-diacetate (CAS NO.30460-34-5) are Monovalent Ion Channels ; Other Sodium Channel Modulators ; Sodium Channel Modulators .The molecular structure of Grayanotoxin iii 6,14-diacetate (CAS NO.30460-34-5) is.

Grayanotoxin iii 6,14-diacetate Uses

 Grayanotoxin iii 6,14-diacetate (CAS NO.30460-34-5) is used as pharmaceutical.

Grayanotoxin iii 6,14-diacetate Toxicity Data With Reference

1.    

ipr-mus LD50:>100 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 35 (1976),303.
2.    

ivn-gpg LD50:2500 µg/kg

    ARTODN    Archives of Toxicology. 44 (1980),259.

Grayanotoxin iii 6,14-diacetate Safety Profile

A poison by intraperitoneal and intravenous route. When heated to decomposition it emits acrid smoke and irritating vapors.
Hazard Codes: ToxicT
Risk Statements: 23/24/25-36/38 
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed. 
R36/38: Irritating to eyes and skin.
Safety Statements: 22-26-36/37/39-45 
S22: Do not breathe dust. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

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