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| Name |
Bleomycin A5 |
EINECS | 234-357-0 |
| CAS No. | 11116-32-8 | Density | 1.56g/cm3 |
| PSA | 721.60000 | LogP | -1.43400 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C57H89 N19 O21 S2 | Boiling Point | °Cat760mmHg |
| Molecular Weight | 1423.73 | Flash Point | °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by intraperitoneal, intravenous, intramuscular, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by an unspecified route: nausea or vomiting, dyspnea, and fever. Mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx. See other bleomycin entries. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Bleomycetin;Bleomycin A5; NSC 350895; Pingyangmycin A5; Zhengguangmycin A5 |
Bleomycin A5 Chemical Properties
Chemical Name: Bleomycin A5
IUPAC NAME: [2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[5-[[1-[2-[4-[4-[3-(4-aminobutylamino)propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate
CAS No.: 11116-32-8
EINECS: 234-357-0
Molecular Formula: C57H89N19O21S2
Molecular Weight: 1440.56 g/mol
Density: 1.56 g/cm3
The chemical synonymous of Bleomycin A5 (CAS No.11116-32-8) are Bleomycinamide, N1-[3-[(4-Aminobutyl)Amino]Propyl]- ; Bleomycetin ; Bleomycin A5 ; N1-(3-((4-Aminobutyl)Amino)Propyl)Bleomycinamide ; Pingyangmycin A5 ; Zhengguanmycin A5
Bleomycin A5 Toxicity Data With Reference
| 1. | cyt-ham:ovr 400 µg/L | HKXUDL Huanjing Kexue Xuebao. Environmental Sciences Journal. 3 (1983),78. | ||
| 2. | sce-ham:ovr 400 µg/L | HKXUDL Huanjing Kexue Xuebao. Environmental Sciences Journal. 3 (1983),78. | ||
| 3. | unr-hmn TDLo:192 mg/kg:GIT,PUL,MET | ANTBAL Antibiotiki. 28 (8)(1983),632. | ||
| 4. | ipr-rat LD50:117 mg/kg | ANTBAL Antibiotiki. 24 (5)(1979),363. | ||
| 5. | ivn-rat LD50:100 mg/kg | ANTBAL Antibiotiki. 24 (5)(1979),363. | ||
| 6. | ims-rat LD50:102 mg/kg | ANTBAL Antibiotiki. 24 (5)(1979),363. | ||
| 7. | orl-mus LD50:840 mg/kg | ANTBAL Antibiotiki. 24 (5)(1979),363. | ||
| 8. | ipr-mus LD50:88 mg/kg | ANTBAL Antibiotiki. 24 (5)(1979),363. | ||
| 9. | scu-mus LD50:77 mg/kg | ANTBAL Antibiotiki. 24 (5)(1979),363. | ||
| 10. | ivn-mus LD50:61,500 µg/kg | ANTBAL Antibiotiki. 24 (5)(1979),363. |
Bleomycin A5 Safety Profile
Poison by intraperitoneal, intravenous, intramuscular, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by an unspecified route: nausea or vomiting, dyspnea, and fever. Mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx. See other bleomycin entries.
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