28437-31-2

Usage

General Description

1,3-Benzodioxole, 5-(3-bromopropyl)-, also known as safrole bromide, is a chemical compound that belongs to the group of benzodioxoles. It is used as an intermediate in the synthesis of various drugs and is also employed in the production of perfumes and flavorings. 1,3-Benzodioxole, 5-(3-bromopropyl)- is classified as a hazardous substance and a potential carcinogen, and it is important to handle it with caution and adhere to proper safety protocols when working with it. Additionally, it is important to be aware of the regulations and guidelines regarding its transportation, storage, and disposal to prevent any environmental contamination or harm to human health.

Upstream product

• 94-59-7 1-allyl-3,4-methylenedioxybenzene 
• 7031-03-0 3-(benzo[d][1,3]dioxol-5-yl)propan-1-ol 
• 7789-60-8 phosphorus tribromide 
• 2815-95-4 3-(1,3 benzodioxol-5-yl)propionic acid 
• 14731-78-3 ethyl 3,4-methylenedioxycinnamate 
• 7116-48-5 3-benzo[1,3]dioxol-5-yl-propionic acid ethyl ester 
• 2373-80-0 3,4-methylenedioxy-trans-cinnamic acid 

Downstream Products

• 587854-63-5 1-benzyl-5-hydroxy-5-[3-(3',4'-methylenedioxyphenyl)propyl]pyrrolidin-2-one 

Relevant academic research and scientific papers

AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF

Provided is a novel amine compound represented by the following formula (I) having a superior peripheral blood lymphocyte decreasing action and superior in the immunosuppressive action, rejection suppressive action and the like, which shows decreased side effects of, for example, bradycardia and the like, or a pharmaceutically acceptable acid addition salt thereof, or a hydrate thereof, or a solvate thereof. wherein each symbol is as defined in the specification.

Spiro cyclisations of N-acyliminium ions involving an aromatic π-nucleophile

Spiro 2-pyrrolidin-5-ones were obtained from N-substituted succinimides by a two-step procedure, involving 5- or 6-endo-trig cyclisation of N-acyliminium ion intermediates with a tethered aromatic π-nucleophile.

Method for treating glaucoma

Methods of using prostaglandin agonists for the reduction of intraocular pressure, and accordingly glaucoma.

Prevention of loss and restoration of bone mass by certain prostaglandin agonists

Prostaglandin agonists of formula (I), in which, for example, A is a sulphonyl or acyl group, B is N or CH, M contains a ring and K and Q are linking groups, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits useful for the treatment of bone disorders including osteoporosis. STR1

Facile Conversion of Alkenes into Alkyl Bromides via Reaction of Organoboranes with Bromine or Bromine Chloride

Organoboranes react with either bromine or bromine chloride in aqueous media to yield the corresponding alkyl bromides under surprisingly mild conditions.The reaction is ideal for the synthesis of functionally substituted organic bromides.Sodium bromide may be utilized as the bromine source via its in situ conversion to bromine chloride by using mild oxidizing agents.

Juvenile hormone mimics

Insect populations are controlled by treating an immature form of the insect with a novel compound possessing juvenile hormone-like activity. Such a compound is one having the formula EQU1 wherein Y is thienyl, phenyl or substituted phenyl. For example, 9-(3,4-methylenedioxyphenyl)-2,6-dimethyl-2,6-nonadiene exhibits very good activity.