Total quantification and extraction of shikimic acid from star anise (llicium verum) using solid-state NMR and cellulose-dissolving aqueous hydroxide solutions
-
Add time:07/20/2019 Source:sciencedirect.com
Many pharmaceutically relevant molecules are still extracted directly from lignocellulosic biomass sources. As this can be a bottleneck in supply, total quantification followed by total extraction are desirable processes to ensure as much as possible is obtained, at the optimal time in the growth cycle. Herein we report the application of solid-state 13C nuclear magnetic resonance (NMR) spectroscopy to quantify shikimic acid present inside Chinese star anise (or star aniseed, llicium verum). Subsequently, methanol soxhlet extraction is compared with conventional aqueous hydroxides (i.e. sodium hydroxide) and cellulose-dissolving aqueous hydroxides (i.e. tetraethylammonium and tetrabutylammonium hydroxide) for shikimic acid isolation. Methanol extraction isolated ca. 6.6±0.1 wt% (wt%) shikimic acid (post-purification), and solid-state NMR confirmed extraction was incomplete even after 72 h. Conversely, dissolution of the star anise at room temperature in tetrabutylammonium hydroxide ([N4444]OH) allowed isolation of ca. 14.0±0.6 wt% shikimic acid (post-purification). Solid state NMR confirmed the star anise initially contained 19±3 wt% shikimic acid, which was quantitatively extracted after dissolution in the aqueous hydroxide solution. The solubility of the star anise and the kinetics of the shikimic acid extraction were also briefly evaluated.
We also recommend Trading Suppliers and Manufacturers of Anisic acid (cas 100-09-4). Pls Click Website Link as below: cas 100-09-4 suppliers
Prev:Crystal Structures of the Free and Anisic acid (cas 100-09-4) Bound Triple Mutant of Phospholipase A2
Next:Formulation and evaluation of anise-based bioadhesive vaginal gels) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Physical and antimicrobial properties of anise oil loaded nanoemulsions on the survival of foodborne pathogens07/28/2019
- Evaluation of antibacterial efficacy of anise wastes against some multidrug resistant bacterial isolates07/27/2019
- Anise, parsley and rocket as nematicidal soil amendments and their impact on non-target soil organisms07/26/2019
- Kinetics of micellar catalysis on oxidation of p-anisaldehyde to p-Anisic acid (cas 100-09-4) in aqueous medium at room temperature07/25/2019
- Optimization and comparison of ultrasound-assisted extraction and microwave-assisted extraction of shikimic acid from Chinese star anise07/24/2019
- Preconcentration of trace lead and iron on activated carbon functionalized by o-Anisic acid (cas 100-09-4) derivatives prior to their determination in environmental samples07/23/2019
- Formulation and evaluation of anise-based bioadhesive vaginal gels07/22/2019
- Crystal Structures of the Free and Anisic acid (cas 100-09-4) Bound Triple Mutant of Phospholipase A207/21/2019
- Transmission of p-Anisic acid (cas 100-09-4) through nanofiltration and goat membranes07/19/2019
-
Health and Chemical more >