top Fluticasone propionate CAS NO.80474-14-2

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Min.Order Quantity:: 1 Gram

Purity:: 99% min

Port:: China main port

Payment Terms:: L/C,T/T,

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Product Details

Keywords

Fluticasone propionate
high purity Fluticasone propionate
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Quick Details

ProName: top Fluticasone propionate
CasNo: 80474-14-2
Molecular Formula: C25H31F3O5S
Appearance: Crystalline
Application: Pharmaceutical intermediates
DeliveryTime: With about 7-10 days after receipt the...
PackAge: as you requested
Port: China main port
ProductionCapacity: 10 Kilogram/Day
Purity: 99% min
Storage: Room temperature
Transportation: by courier
LimitNum: 1 Gram
Transportation: by courier

Superiority

our company was built in 2009 with an iso certificate.in the past 5 years, we have grown up as a famous fine chemicals supplier in china and we had established stable business relationships with samsung,lg,merck,thermo fisher scientific and so on.our main business covers the fields below:

1.noble metal catalysts (pt.pd...)

2.organic phosphine ligands (tert-butyl-phosphine.cyclohexyl-phosphine...)

3.oled intermediates (fluorene,carbazole,boric acid...)

4.customs synthesis

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Details

product name:	fluticasone propionate
synonyms:	s-fluoromethyl-6alpha,9alpha-difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17alpha-propionyloxyandrosta-1,4-diene-17beta-carbothioate;-17-(1-oxopropoxy)-,s-(fluoromethyl)ester,(6-alpha,11-beta,16-alpha,17-alph;androsta-1,4-diene-17-carbothioicacid,6,9-difluoro-11-hydroxy-16-methyl-3-oxo;cci18781;fluticasone17-propionate;flutide;(6a,11b,16a,17a)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid fluoromethyl ester;(6 alpha,11 beta,16 alpha,17 alpha)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid fluoromethyl ester
cas:	80474-14-2
mf:	c25h31f3o5s
mw:	500.57
einecs:
product categories:	biochemistry;hydroxyketosteroids;steroids;intermediates & fine chemicals;pharmaceuticals;fluticasone;steroid and hormone;hivid;hormone drugs
mol file:	80474-14-2.mol

fluticasone propionate chemical properties

melting point	275 °c
alpha	d +30° (c = 0.35)
refractive index	31 ° (c=1, dioxane)
storage temp.	store at rt
solubility	dmso: ≥10 mg/ml
form	solid
color	white
merck	14,4211
inchikey	wmwtyokrwggjoa-censzejfsa-n
cas database reference	80474-14-2(cas database reference)

safety information

safety statements	22-24/25
wgk germany	2
rtecs	bv7980000
hs code	29372900

msds information

provider	language
fluticasone propionate	english
sigmaaldrich	english

fluticasone propionate usage and synthesis

chemical properties	crystalline solid
uses	an antiallergic and anti inflammatory
uses	a derivative of flumethasone. an antiallergic; anti-asthmatic; anti-inflammatory.
uses	antiviral
uses	atorvastatin intermediate
uses	a high-affinity, selective glucocorticoid receptor agonist
definition	chebi: a trifluorinated corticosteroid that consits of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a propionyl s bstituent at position 17; has anti-inflammatory, anti-asthmatic and anti-allergic activity.
biological activity	high affinity, selective glucocorticoid receptor agonist (k d = 0.5 nm). potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis (ec 50 = 3.7 nm) in vitro . inhibits mast cell accumulation in nasal mucosa following topical administration. lipophilic, clinically-used anti-inflammatory agent with low oral bioavailability.