99439-28-8

Basic information

• Product Name: Fumed silica
• Synonyms: Quartz; acticel; cab-o-sil; cab-o-sperse; Fumed Silicas; Silica, fused; Silica, vitreous; flatting agents; flatting agent; delustering agent; MATTING AGENT; Aerosil; Amorphous silica; Fumed silica; Silica; Quartz sand
• CAS NO: 99439-28-8
• Molecular Formula: O2Si
• Molecular Weight: 60.084
• EINECS: 215-683-2;238-878-4;262-373-8;231-545-4
• Mol File: 99439-28-8.mol
• Article Data: 123

Chemical Properties

• Melting Point: 1610℃
• Boiling Point: 2230℃
• Appearance: /
• Density: 2.2
• Water Solubility: insoluble
• CAS DataBase Reference: Fumed silica(CAS DataBase Reference)
• NIST Chemistry Reference: Fumed silica(99439-28-8)
• EPA Substance Registry System: Fumed silica(99439-28-8)

Safety Data

• Statements: R37:Irritating to respiratory system.
• Safety Statements: S24/25:
• Hazardous Substances Data: 99439-28-8(Hazardous Substances Data)

Usage

Description

Fumed silica, also known as pyrogenic silica, is a fine, amorphous powder composed of microscopic particles of silicon dioxide. It is produced by burning silicon tetrachloride in a flame of hydrogen and oxygen, resulting in the formation of nanoscale particles that aggregate into larger aggregates. Fumed silica is valued for its high surface area, excellent reinforcement and strengthening properties, and its ability to improve the flow and stability of formulations. It is also non-toxic, chemically inert, and heat resistant, making it suitable for a wide range of applications.

Uses

Used in Adhesives and Sealants:
Fumed silica is used as a thickening agent and rheology modifier for improving the flow and stability of adhesives and sealants. Its high surface area provides excellent reinforcement and strengthening properties, enhancing the performance and durability of these products.
Used in Coatings:
In the coatings industry, fumed silica is used as a rheology modifier to control the flow and leveling of coatings. It also helps in improving the mechanical properties and durability of the coatings, providing a smoother and more uniform finish.
Used in Plastics:
Fumed silica is used as a reinforcing agent in plastics to enhance their mechanical properties, such as tensile strength, impact resistance, and heat resistance. Its high surface area and excellent reinforcing properties make it an ideal additive for improving the performance of plastic materials.
Used in Cosmetics and Personal Care Products:
Fumed silica is used as a thickening agent, anti-caking agent, and rheology modifier in cosmetics and personal care products, such as creams, lotions, and powders. Its ability to improve the texture and stability of these products makes it a valuable ingredient in the formulation of various cosmetic and personal care products.
Used in Food and Beverage Industry:
In the food and beverage industry, fumed silica is used as an anti-caking agent and thickening agent in various products, such as powdered drinks, sauces, and condiments. Its ability to improve the flow and stability of these products ensures a consistent quality and texture.
Used in Pharmaceutical Industry:
Fumed silica is used as a carrier and excipient in the pharmaceutical industry, particularly in the formulation of tablets, capsules, and powders. Its high surface area and excellent reinforcing properties contribute to improved drug delivery and stability of pharmaceutical formulations.
Used in Electronics and Electrical Industry:
In the electronics and electrical industry, fumed silica is used as an insulating material and a filler in various applications, such as in the production of insulating varnishes, adhesives, and encapsulants. Its high surface area and excellent reinforcing properties provide improved electrical insulation and thermal stability.
Used in Automotive Industry:
Fumed silica is used in the automotive industry as a reinforcing agent and rheology modifier in various applications, such as in the production of tires, seals, and gaskets. Its high surface area and excellent reinforcing properties contribute to improved performance, durability, and heat resistance of these components.
Used in Construction Industry:
In the construction industry, fumed silica is used as a thickening agent, anti-caking agent, and rheology modifier in various construction materials, such as concrete, mortar, and plaster. Its ability to improve the flow and stability of these materials ensures a consistent quality and performance in construction applications.

InChI:InChI=1/O2Si/c1-3-2

Upstream product

• 57-09-0 cetyltrimethylammonim bromide 
• 1470-94-6 5-hydroxy-2,3-dihydro-1H-indene 
• 105-13-5 4-Methoxybenzyl alcohol 
• 260-94-6 acridine 
• 98-59-9 p-toluenesulfonyl chloride 
• 124-30-1 1-aminooctadecane 
• 78-94-4 methyl vinyl ketone 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 579-75-9 2-Methoxybenzoic acid 
• 586-38-9 3-Methoxybenzoic acid 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 1126-79-0 n-butyl phenyl ether 
• 38186-51-5 diethyl (4-bromobenzyl)phosphonate 
• 1363382-39-1 tert-butyl 6-oxo-2-azaspiro [3.4] octane-2-carboxylate 

Downstream Products

• 134892-42-5 SKF 190851 
• 81864-29-1 N-(2,2-dimethylbenzo[1,3]dioxol-5-yl)acetamide 
• 73671-86-0 (4aR,4bS,6aS,7S,9aS,9bS,11aR)-1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinoline-7-carboxylic acid diethylamide 

Relevant articles and documents

CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS

Compounds of Formula (I), and pharmaceutically acceptable salts, isotopes, N-oxides, solvates, and stereoisomers thereof, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to depression, major depressive disorder, treatment resistant depression, anxious depression, autism spectrum disorders, Asperger syndrome, and bipolar disorder), cancers and eye conditions: wherein R1, , R3, and L are as defined herein.

COMPOUND FOR INHIBITING PGE2/EP4 SIGNALING TRANSDUCTION INHIBITING, PREPARATION METHOD THEREFOR, AND MEDICAL USES THEREOF

A compound of formula (I), a preparation method therefor, a pharmaceutical composition containing a derivative thereof, and the therapeutic uses thereof, especially inhibiting PGE2/EP4 signalling transduction and the uses thereof for treating cancer, acute or chronic pain, migraine, osteoarthritis, rheumatoid arthritis, gout, bursitis, ankylosing spondylitis, primary dysmenorrhea, tumour or arteriosclerosis.

TEMPERATURE-SENSITIVE NANO SILVER CONTROLLED-RELEASE SMART ANTIBACTERIAL COATING AND PREPARATION METHOD THEREFOR

This present invention discloses a temperature-sensitive nano-silver controlled release antibacterial coating composite, which is comprises: water, acrylic, polyurethane resin, temperature-sensitive nano-silver controlled release antibacterial agent, dispersant, curing agent, defoamer, filming additive and leveling agent. By adsorbing nano silver particles into the pores of mesoporous SiO2 modified by poly N-isopropyl acrylamide, we successfully prepared a temperature-sensitive nano-silver controlled release antibacterial agent. By adding the prepared agent to the conventional coating composite, we achieved “on-off” control of the antibacterial properties of coating composite. Through the control of temperature, the release of nano-silver in the mesoporous nano-silica of the coating film layer is controlled. This control method is not only to protect the nano-silver, but also to adjust the strength of the anti-bacterial properties according to the actual demands and improve the use-efficiency of nano silver particles. This invention is in line with the new concept of “Intelligent Age” in the 21st century.