95216-56-1

Basic information

• Product Name: Benzoic acid, 5-methyl-2-(phenylamino)-
• CAS NO: 95216-56-1
• Molecular Formula: C14H13NO2
• Molecular Weight: 227.263
• Mol File: 95216-56-1.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 5-methyl-2-(phenylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 5-methyl-2-(phenylamino)-(95216-56-1)
• EPA Substance Registry System: Benzoic acid, 5-methyl-2-(phenylamino)-(95216-56-1)

Safety Data

• Hazardous Substances Data: 95216-56-1(Hazardous Substances Data)

Upstream product

• 2941-78-8 2-Amino-5-methylbenzoic acid 
• 108-86-1 bromobenzene 
• 52548-14-8 2-iodoyl-5-methylbenzoic acid 
• 62-53-3 aniline 
• 6967-82-4 2-bromo-5-methylbenzoic acid 

Downstream Products

• 95216-65-2 5-methyl-2-anilinobenzamide 
• 70344-62-6 2-Isopropyl-6-methyl-1-phenyl-1H-quinazolin-4-one 
• 1428865-10-4 methyl 5-methyl-2-(methyl(phenyl)amino)benzoate 
• 1428865-35-3 5-methyl-2-(methyl(phenyl)amino)benzaldehyde 
• 1428865-23-9 C₁₅H₁₇NO 

Relevant articles and documents

Syntheses and evaluation of new acridone derivatives for selective binding of oncogene c-: Myc promoter i-motifs in gene transcriptional regulation

We synthesized a series of acridone derivatives for specific binding ligands of i-motifs. Subsequent evaluations showed that B19 could selectively bind to and stabilize the c-myc promoter i-motif without significant binding to the G-quadruplex and duplex

Light-Driven Intramolecular C?N Cross-Coupling via a Long-Lived Photoactive Photoisomer Complex

Reported herein is a visible-light-driven intramolecular C?N cross-coupling reaction under mild reaction conditions (metal- and photocatalyst-free, at room temperature) via a long-lived photoactive photoisomer complex. This strategy was used to rapidly prepare the N-substituted polycyclic quinazolinone derivatives with a broad substrate scope (>50 examples) and further exploited to synthesize the natural products tryptanthrin, rutaecarpine, and their analogues. The success of gram-scale synthesis and solar-driven transformation, as well as promising tumor-suppressing biological activity, proves the potential of this strategy for practical applications. Mechanistic investigations, including control experiments, DFT calculations, UV-vis spectroscopy, EPR, and X-ray single-crystal structure of the key intermediate, provides insight into the mechanism.

NIS-mediated intramolecular oxidative α-functionalization of tertiary amines: Transition metal-free synthesis of 1,2-dihydro-(4H)-3,1-benzoxazin-4-one derivatives

A novel method for direct α-functionalization of tertiary amines via NIS-mediated oxidative C-O bond formation, where NIS serves as both an oxidant and an iodination reagent, has been developed. The method provides easy access to either iodinated or non-iodinated 1,2-dihydro-(4H)-3,1-benzoxazin-4-ones, depending on the nature of the reactant, via a regioselective transition metal-free approach. This journal is