939759-12-3 Usage
Description
6-Bromo-2,3,4,5-tetrahydro-1H-benzo[b]azepine is a chemical compound belonging to the benzazepine group, characterized by its molecular formula C11H12BrN. 6-BroMo-2,3,4,5-tetrahydro-1H-benzo[b]azepine features a bromine atom attached to the carbon ring, making it a derivative of the benzazepine family. It has garnered interest due to its potential pharmacological properties and its role as a precursor in the synthesis of therapeutic agents. Furthermore, it has been explored as a building block in organic synthesis and medicinal chemistry, with its specific properties and applications varying based on its use in research and development.
Uses
Used in Pharmaceutical Synthesis:
6-Bromo-2,3,4,5-tetrahydro-1H-benzo[b]azepine serves as a valuable precursor in the synthesis of various therapeutic agents. Its unique structure and bromine atom attachment contribute to the development of new drugs with potential applications in treating different medical conditions.
Used in Organic Synthesis:
As a building block in organic synthesis, 6-Bromo-2,3,4,5-tetrahydro-1H-benzo[b]azepine is utilized for creating complex organic molecules. Its presence in these molecules can influence their properties and reactivity, making it a useful component in the synthesis of specialty chemicals and materials.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 6-Bromo-2,3,4,5-tetrahydro-1H-benzo[b]azepine is investigated for its potential to contribute to the discovery and design of new pharmaceutical compounds. Its structural features may offer advantages in the development of drugs with improved efficacy, selectivity, and safety profiles.
Used in Research and Development:
6-Bromo-2,3,4,5-tetrahydro-1H-benzo[b]azepine is employed in research and development settings to explore its potential applications and properties. This may include studying its interactions with biological targets, assessing its pharmacological activity, and optimizing its synthesis and production methods for various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 939759-12-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,9,7,5 and 9 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 939759-12:
(8*9)+(7*3)+(6*9)+(5*7)+(4*5)+(3*9)+(2*1)+(1*2)=233
233 % 10 = 3
So 939759-12-3 is a valid CAS Registry Number.
939759-12-3Relevant articles and documents
Discovery of a lead series of potent benzodiazepine 5-HT2C receptor agonists with high selectivity in functional and binding assays
Dang, Huong,Feichtinger, Konrad,Frazer, John,Grottick, Andrew J.,Kasem, Michelle,Le, Minh,Lehman, Juerg,Morgan, Michael E.,Ren, Albert,Sage, Carleton R.,Schrader, Thomas O.,Semple, Graeme,Unett, David J.,Whelan, Kevin T.,Wong, Amy,Zhu, Xiuwen
supporting information, (2020/01/22)
A series of potential new 5-HT2 receptor scaffolds based on a simplification of the clinically studied, 5-HT2CR agonist vabicaserin, were designed. An in vivo feeding assay early in our screening process played an instrumental part in the lead identification process, leading us to focus on a 6,5,7-tricyclic scaffold. A subsequent early SAR investigation provided potent agonists of the 5-HT2C receptor that were highly selective in both functional and binding assays, had good rat PK properties and that significantly reduced acute food intake in the rat.
