93844-98-5

Basic information

• Product Name: 2-(pyridin-4-yl)pyrazine
• Synonyms: 2-(pyridin-4-yl)pyrazine
• CAS NO: 93844-98-5
• Molecular Weight: 157.175
• Mol File: 93844-98-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 87.6-88.4 °C
• Boiling Point: 287.3±25.0 °C(Predicted)
• Density: 1.169±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-(pyridin-4-yl)pyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(pyridin-4-yl)pyrazine(93844-98-5)
• EPA Substance Registry System: 2-(pyridin-4-yl)pyrazine(93844-98-5)

Safety Data

• Hazardous Substances Data: 93844-98-5(Hazardous Substances Data)

Usage

General Description

2-(pyridin-4-yl)pyrazine is a chemical compound with the molecular formula C10H8N4. It is a heterocyclic organic compound with a pyrazine ring fused to a pyridine ring. 2-(pyridin-4-yl)pyrazine is commonly used in the pharmaceutical and chemical industries and has potential applications in drug discovery and development. It exhibits biological activity and has been studied for its potential therapeutic properties. Additionally, it is used as a building block in the synthesis of other organic compounds. 2-(pyridin-4-yl)pyrazine is a versatile compound with diverse potential applications in various fields.

Upstream product

• 14508-49-7 2-chloropyrazin 
• 1692-15-5 4-pyridylboronic acid 
• 56423-63-3 2-bromopyrazine 
• 93845-13-7 C₁₈H₁₃N₃O₂ 
• 110-86-1 pyridine 

Relevant articles and documents

Solvent-free, palladium-catalyzed Suzuki-Miyaura cross-couplings of aryl chlorides with arylboronic acids

Pd(MeCN)2Cl2/PCy3 was found to be an efficient catalytic system for the Suzuki-Miyaura cross-couplings of aryl chlorides with arylboronic acids under solvent-free conditions. Furthermore, the presence of the conventional solvents had deleterious effect on the reaction. In the presence of Pd(MeCN)2Cl2, PCy3, and TBAF (tetra-n-butylammonium fluoride), a number of aryl chlorides including heteroaryl chlorides were coupled with arylboronic acids or heteroarylboronic acids smoothly to afford the corresponding products in moderate to excellent yields. Copyright Taylor & Francis Group, LLC.

Pd(OAc)2/DABCO-catalyzed Suzuki-Miyaura cross-coupling reaction in DMF

The scope and limitations of the Pd(OAc)2/DABCO (1,4-diaza-bicyclo[2.2.2]octane)-catalyzed Suzuki-Miyaura cross-coupling reactions have been demonstrated. The results showed that the effect of solvent had a fundamental influence on the reaction. In the presence of Pd(OAc)2 and DABCO, both aryl bromides and aryl chlorides all worked well with arylboronic acids to form biaryls, heteroaryl-aryls, and biheteroaryls in moderate to excellent yields using DMF as the solvent. Additionally, the reactions of aryl bromides were conducted under relatively mild conditions.