931398-67-3

Basic information

• Product Name: C₂₀H₂₈N₂O₅
• Synonyms: C₂₀H₂₈N₂O₅
• CAS NO: 931398-67-3
• Molecular Weight: 376.453
• Mol File: 931398-67-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₈N₂O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₈N₂O₅(931398-67-3)
• EPA Substance Registry System: C₂₀H₂₈N₂O₅(931398-67-3)

Safety Data

• Hazardous Substances Data: 931398-67-3(Hazardous Substances Data)

Upstream product

• 67387-76-2 3-cyclopentyloxy-4-methoxybenzylaldehyde 
• 137-43-9 Cyclopentyl bromide 
• 621-59-0 isovanillin 
• 1772-43-6 2,4,4-trimethyl oxazoline 
• 133332-47-5 2-(cyclopentyloxy)-1-methoxy-4-[(E)-2-nitroethenyl]benzene 

Downstream Products

• 936567-24-7 ethyl 3-(3-(cyclopentyloxy)-4-methoxyphenyl)-4-nitrobutanoate 
• 61413-54-5 Rolipram 

Relevant articles and documents

Conjugated addition of bis(oxazolinyl)zinc to substituted 2-nitrovinyl benzenes: an alternative synthesis of (±)-Rolipram

In this letter we present a new 2,4,4-trimethyl-2-oxazoline anion-zinc derivative that has a remarkable thermal stability when compared with the corresponding cyanocuprate counterpart. The yields from conjugated addition to several 2-nitrovinyl benzenes are moderate to good and the reaction itself is easier to execute and cleaner. As an application, this methodology was applied to an alternative synthesis of (±)-Rolipram, a drug with several interesting biological activities.