92870-05-8

Basic information

• Product Name: 4-butyryl-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
• Synonyms: 4-butyryl-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
• CAS NO: 92870-05-8
• Molecular Weight: 258.32
• Mol File: 92870-05-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-butyryl-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-butyryl-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one(92870-05-8)
• EPA Substance Registry System: 4-butyryl-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one(92870-05-8)

Safety Data

• Hazardous Substances Data: 92870-05-8(Hazardous Substances Data)

Upstream product

• 60-80-0 antipyrine 
• 1821-02-9 2-oxopentanoic acid 
• 100-63-0 phenylhydrazine 
• 89-25-8 edaravone 
• 141-75-3 butyryl chloride 

Relevant articles and documents

Copper/Persulfate-Promoted Oxidative Decarboxylative C?H Acylation of Pyrazolones with α-Oxocarboxylic Acids: Direct Access to 4-Acylpyrazolones under Mild Conditions

A facile and efficient oxidative C?H acylation of N-substituted pyrazolones using α-oxocarboxylic acids as an acyl group source was developed. A combination of Cu(OAc)2 and K2S2O8 enables the reaction to proceed smoothly under air and provides a wide array of 4-acylpyrazolone products in moderate to excellent yields. The mechanism of this transformation is believed to proceed via a copper-induced decarboxylation to form the acyl-copper species. This method provides a convenient and useful route for a direct installation of an acyl moiety into bioactive pyrazolone derivatives, which can be further utilized in many applications. (Figure presented.).