906651-46-5

Basic information

• Product Name: tert-butyl (E)-(2S,3S)-3-[(S)-1-tert-butoxycarbonyl-2-(4-but-2-ynyloxy-phenyl)-ethylcarbamoyl]-2-hydroxy-2-(2-hydroxy-ethyl)-12-oxo-nonadec-4-enoate
• Synonyms: tert-butyl (E)-(2S,3S)-3-[(S)-1-tert-butoxycarbonyl-2-(4-but-2-ynyloxy-phenyl)-ethylcarbamoyl]-2-hydroxy-2-(2-hydroxy-ethyl)-12-oxo-nonadec-4-enoate
• CAS NO: 906651-46-5
• Molecular Weight: 742.006
• Mol File: 906651-46-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl (E)-(2S,3S)-3-[(S)-1-tert-butoxycarbonyl-2-(4-but-2-ynyloxy-phenyl)-ethylcarbamoyl]-2-hydroxy-2-(2-hydroxy-ethyl)-12-oxo-nonadec-4-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (E)-(2S,3S)-3-[(S)-1-tert-butoxycarbonyl-2-(4-but-2-ynyloxy-phenyl)-ethylcarbamoyl]-2-hydroxy-2-(2-hydroxy-ethyl)-12-oxo-nonadec-4-enoate(906651-46-5)
• EPA Substance Registry System: tert-butyl (E)-(2S,3S)-3-[(S)-1-tert-butoxycarbonyl-2-(4-but-2-ynyloxy-phenyl)-ethylcarbamoyl]-2-hydroxy-2-(2-hydroxy-ethyl)-12-oxo-nonadec-4-enoate(906651-46-5)

Safety Data

• Hazardous Substances Data: 906651-46-5(Hazardous Substances Data)

Upstream product

• 16874-12-7 Tyr(tBu) 
• 18938-60-8 (S)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanoate 
• 827036-34-0 tert-butyl (S)-3-(4-(but-2-yn-1-yloxy)phenyl)-2-((tertbutoxycarbonyl)amino)propanoate 
• 827036-35-1 tert-butyl (S)-2-amino-3-(4-(but-2-yn-1-yloxy)phenyl)-propanoate hydrochloride 
• 906651-45-4 C₅₉H₈₅NO₉Si 

Downstream Products

• 906651-47-6 1-tert-butyl (S)-2-{(E)-(S)-1-[(S)-1-tert-butoxycarbonyl-2-(4-but-2-ynyloxy-phenyl)-ethylcarbamoyl]-10-oxo-heptadec-2-enyl}-2-hydroxy-succinate 
• 827034-92-4 (S)-2-((S,E)-1-(((S)-2-(4-(but-2-yn-1-yloxy)phenyl)-1-carboxyethyl)amino)-1,11-dioxooctadec-3-en-2-yl)-2-hydroxysuccinic acid 

Relevant articles and documents

Development of a Kilogram-Scale Synthesis of a Novel Anti-HCV Agent, CH4930808

Herein, we report the kilogram-scale synthesis of CH4930808 (1), a novel anti-hepatitis C virus agent. While pursuing improved productivity using many through-process strategies, we conducted scrupulous impurity control. Finally, we successfully developed