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90597-22-1

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  • 2(1H)-Pyrimidinone, 4-amino-1-(4,5-dihydroxy-3-(hydroxymethyl)-2-cyclopenten-1-yl)-, (1R-(1-alpha,4-beta,5-beta))-

    Cas No: 90597-22-1

  • USD $ 3.0-3.0 / Kilogram

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  • Dayang Chem (Hangzhou) Co.,Ltd.
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  • 4-amino-1-[(1R,4R,5S)-4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]pyrimidin-2-one

    Cas No: 90597-22-1

  • USD $ 18.0-20.0 / Kilogram

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  • 4-amino-1-[(1R,4R,5S)-4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]pyrimidin-2-one

    Cas No: 90597-22-1

  • USD $ 1.5-1.5 / Metric Ton

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  • 90597-22-1 Structure

  • Basic information

    1. Product Name: cyclopentenyl cytosine
    2. Synonyms: cyclopentenyl cytosine;1-[(1β)-4β-(Hydroxymethyl)-2α,3α-dihydroxy-4-cyclopentenyl]cytosine;4',4'-O-Didehydro-4'-O-carbacytidine;4-Amino-1-[(1R,4R,5S)-4β,5β-dihydroxy-3-hydroxymethyl-2-cyclopentenyl]pyrimidin-2(1H)-one;CPEC;CPE-C;NSC-375575;1-[(1R)-2β,3β-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1β-yl]cytosine
    3. CAS NO:90597-22-1
    4. Molecular Formula: C10H13N3O4
    5. Molecular Weight: 239.22800
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 90597-22-1.mol
    9. Article Data: 4

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 508.4oC at 760 mmHg
    3. Flash Point: 261.3oC
    4. Appearance: /
    5. Density: 1.73g/cm3
    6. Vapor Pressure: 1.82E-12mmHg at 25°C
    7. Refractive Index: 1.743
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: cyclopentenyl cytosine(CAS DataBase Reference)
    11. NIST Chemistry Reference: cyclopentenyl cytosine(90597-22-1)
    12. EPA Substance Registry System: cyclopentenyl cytosine(90597-22-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 90597-22-1(Hazardous Substances Data)

90597-22-1 Usage

Description

Cyclopentenyl cytosine is a chemical compound with potential antitumor properties. It is known for its ability to induce senescence in breast cancer cells through nucleolar stress response and activation of the p53 protein, which plays a crucial role in controlling cell cycle and preventing tumor formation.

Uses

Used in Anticancer Applications:
Cyclopentenyl cytosine is used as an anticancer agent for its ability to induce senescence in breast cancer cells. This is achieved through the nucleolar stress response and activation of the p53 protein, which helps in inhibiting tumor growth and progression.
Additionally, cyclopentenyl cytosine exhibits antitumor activity, making it a promising candidate for further research and development in the field of cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 90597-22-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,5,9 and 7 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 90597-22:
(7*9)+(6*0)+(5*5)+(4*9)+(3*7)+(2*2)+(1*2)=151
151 % 10 = 1
So 90597-22-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H13N3O4/c11-7-1-2-13(10(17)12-7)6-3-5(4-14)8(15)9(6)16/h1-3,6,8-9,14-16H,4H2,(H2,11,12,17)/t6-,8-,9+/m1/s1

90597-22-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-amino-1-[(1R,4R,5S)-4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]pyrimidin-2-one

1.2 Other means of identification

Product number -
Other names 4-amino-1-[(1'R,2'S,3'R)-2',3'-dihydroxy-4'-hydroxymethyl-4'-cyclopenten-1'-yl]-2(1H)pyrimidinone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:90597-22-1 SDS

90597-22-1Upstream product

90597-22-1Downstream Products

90597-22-1Relevant articles and documents

Enantiomeric synthesis of D- and L-cyclopentenyl nucleosides and their antiviral activity against HIV and West Nile virus

Song,Paul,Choo,Morrey,Sidwell,Schinazi,Chu

, p. 3985 - 3993 (2007/10/03)

Enantiomeric synthesis of D- and L-cyclopentenyl nucleosides and their antiviral activity against HIV and West Nile virus are described. The key intermediate (-)- and (+)-cyclopentenyl alcohols (7 and 15) were prepared from D-γ-ribonolactone and D-ribose,

ENANTIOSELECTIVE SYNTHESIS OF NEW ANALOGS OF NEPLANOCIN A AND THEIR BIOLOGICAL ACTIVITY

Arita, Masafumi,Okumoto, Takeki,Saito, Tadamasa,Hoshino, Yukio,Fukukawa, Kiyofumi,et al.

, p. 233 - 258 (2007/10/02)

Various carbocyclic nucleosides analogs of neplanocin A (such as 5-aminoimidazole-4-carboxamide riboside, uridine, 5-iodouridine, 4-thiouridine, cytidine, thymidine, 2'-deoxyguanosine, ribofuranosylthymine, a 2,2'-anhydroderivative, 2'-deoxycytidine, 2'-d

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