90244-12-5

Basic information

• Product Name: (3R,4R)-4-{(1R)-1-ethoxycarbonylethoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-2-methylprop-1-enyl)azetidin-2-one
• Synonyms: (3R,4R)-4-{(1R)-1-ethoxycarbonylethoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-2-methylprop-1-enyl)azetidin-2-one
• CAS NO: 90244-12-5
• Molecular Weight: 570.642
• Mol File: 90244-12-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3R,4R)-4-{(1R)-1-ethoxycarbonylethoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-2-methylprop-1-enyl)azetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R)-4-{(1R)-1-ethoxycarbonylethoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-2-methylprop-1-enyl)azetidin-2-one(90244-12-5)
• EPA Substance Registry System: (3R,4R)-4-{(1R)-1-ethoxycarbonylethoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-2-methylprop-1-enyl)azetidin-2-one(90244-12-5)

Safety Data

• Hazardous Substances Data: 90244-12-5(Hazardous Substances Data)

Upstream product

• 7699-00-5 (R)-Ethyl lactate 
• 68057-04-5 (1R,5S)-3-phenyl-6-(1-diphenylmethoxycarbonyl-2-methylprop-1-enyl)-7-oxo-4-oxa-2,6-diazabicyclo[3.2.0]hept-2-ene 

Downstream Products

• 130793-11-2 Sodium; (R)-2-((2R,3R)-3-benzoylamino-4-oxo-azetidin-2-yloxy)-propionate 
• 90211-58-8 (4R,6R,7R)-7-Benzoylamino-4-methyl-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 90244-15-8 (4S,6R,7R)-7-Benzoylamino-4-methyl-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 90211-63-5 (4R,6R,7R)-7-Benzoylamino-4-methyl-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 130793-05-4 (4S,6R,7R)-7-Benzoylamino-4-methyl-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 90211-52-2 (3R,4R)-4-{(1S)-1-ethoxycarbonylethoxy)-3-benzamido-1-(1-diphenylmethoxycarbonyl-1-chloromethyl)azetidin-2-one 
• 90211-52-2 (3R,4R)-4-{(1R)-1-ethoxycarbonylethoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-1-chloromethyl}azetidin-2-one 
• 90211-51-1 (3R,4R)-4-{(1S)-1-ethoxycarbonylethoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-1-hydroxymethyl)-azetidin-2-one 
• 130793-06-5 (4R,6R,7R)-3-Acetoxymethyl-7-benzoylamino-4-methyl-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 130675-29-5 (4S,6R,7R)-3-Acetoxymethyl-7-benzoylamino-4-methyl-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 130793-07-6 (4S,6R,7R)-7-Benzoylamino-3-chloromethyl-4-methyl-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 130675-33-1 N-[(2R,3R)-2-((R)-2-Imidazol-1-yl-1-methyl-2-oxo-ethoxy)-4-oxo-azetidin-3-yl]-benzamide 
• 90211-61-3 (3R,4R)-4-{(1S)-3-(1-methyl-1H-tetrazole-5-yl)thio-2-oxo-1-methylpropoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-1-triphenylphosphoranylidenemethyl)-azetidin-2-one 
• 90318-96-0 {(2R,3R)-3-Benzoylamino-2-[(R)-1-methyl-3-(1-methyl-1H-tetrazol-5-ylsulfanyl)-2-oxo-propoxy]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid benzhydryl ester 

Relevant articles and documents

NOVEL 2-METHYL-1-OXACEPHALOSPORINS 1. SYNTHESIS OF 2-METHYL-3-NOR-1-OXACEPHEM NUCLEUS

The 2α- and 2β-methyl-1-oxacephems were synthesized stereoselectively starting from (3R,4S)-oxazolinoazetidinone by reaction with chiral alcohols followed by intramolecular carbene insertion of α-diazo-β-keto intermediates.